C9ORF95

Alternative Names: Nicotinamide riboside kinase 1, NRK 1, NmR-K 1, Nicotinic acid riboside kinase 1, Ribosylnicotinamide kinase 1, RNK 1, Ribosylnicotinic acid kinase 1, NMRK1, C9orf95, NRK1, bA235O14.2, RP11-235O14.2.

C9ORF95, a member of the uridine kinase family, has an important role in the production of NAD+, which is essential for various life processes. NAD+ functions as a coenzyme and provides ADPribosyl groups for multiple reactions, some of which have been shown to have anti-aging effects. The vitamin precursors of NAD+ are nicotinic acid and nicotinamide. C9ORF95 facilitates the conversion of nicotinamide riboside and nicotinic acid riboside into nicotinamide mononucleotide and nicotinic acid mononucleotide. Additionally, C9ORF95 is involved in the phosphorylation of antitumor drugs called tiazofurin and 3-deazaguanosine.

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  • Sku: PSB-pro-1116-5µg
  • Vendor: ProSpec-Tany
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Safety Data Sheet
UniProt Listing
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Product Details

Product Description

Recombinant Human Chromosome 9 Open Reading Frame 95 (C9orf95) is a protein-coding gene located on chromosome 9 in humans. Belonging to the C9orf family, this gene encodes a protein that plays a role in various cellular processes. With a molecular weight of approximately X kDa, C9orf95 is involved in the regulation of gene expression and has been implicated in certain diseases. Understanding the function and mechanism of C9orf95 can provide valuable insights into the intricate workings of cellular processes.

Current Lead Time

7-14 Days

Product Specifications

Species
 Human
Expression System E. coli
Purity 90% by SDS-PAGE
Activity
 Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
 25.6 kDa
Structure Monomer
Endotoxin Concentration
 Not Available
Purification Method Not Available
Form
 Frozen
Formulation C9ORF95 protein solution (0.5mg/ml) containing 20mM Tris-HCl buffer, pH8.0, 10% glycerol, 2mM DTT and 200mM NaCl.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

MGSSHHHHHH SSGLVPRGSH MGSMKTFIIG ISGVTNSGKT TLAKNLQKHL PNCSVISQDD FFKPESEIET DKNGFLQYDV LEALNMEKMM SAISCWMESA RHSVVSTDQE SAEEIPILII EGFLLFNYKP LDTIWNRSYF LTIPYEECKR RRSTRVYQPP DSPGYFDGHV WPMYLKYRQE MQDITWEVVY LDGTKSEEDL FLQVYEDLIQ ELAKQKCLQV TA.

Storage Instruction

Reconstituted store at -20°C or -80°C.We recommend that single use aliquots are prepared to avoid freeze-thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution
​

References

Not Available
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C9ORF95
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