C1QTNF5

Alternative Names: CTRP5, MFRP, CTRP5, MFRP

The gene C1QTNF5 encodes a type of collagen that is found in the sub-retinal pigment epithelium, ciliary epithelium, and adipose tissue. This gene is more highly expressed in mtDNA-depleted myocytes and can stimulate the phosphorylation of AMP activated protein kinase. C1QTNF5 plays a role in the adhesion of the retinal pigment epithelium to the Bruch Membrane. Mutations in C1QTNF5 have been linked to the development of late-onset retinal degeneration.

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  • Sku: PSB-pro-2599-2µg
  • Vendor: ProSpec-Tany
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Title

Product Details

Product Description

Recombinant Human Complement C1q Tumor Necrosis Factor-Related Protein 5 (C1QTNF5) is a member of the C1q/TNF-related protein family. This protein is involved in various physiological processes, including adipocyte differentiation, glucose metabolism, and insulin sensitivity. C1QTNF5 has a molecular weight of approximately X kDa. Understanding the role of C1QTNF5 in these processes may provide insights into the development of therapeutic strategies for metabolic disorders.

Current Lead Time

7-14 Days

Product Specifications

Species
Human
Expression System E. coli
Purity 85.0 % by SDS-PAGE
Activity
Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
26.4 kDa
Structure Homodimer
Endotoxin Concentration
Not Available
Purification Method Not Available
Form
Frozen
Formulation The C1QTNF5 protein solution (0.25 mg/ml) is formulated in 20mM Tris-HCl buffer (pH8.5) containing 30% glyceroland 0.2M NaCl.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

MGSSHHHHHH SSGLVPRGSH MGSHMSPPLD DNKIPSLCPG HPGLPGTPGH HGSQGLPGRDGRDGRDGAPG APGEKGEGGR PGLPGPRGDP GPRGEAGPAG PTGPAGECSV PPRSAFSAKRSESRVPPPSD APLPFDRVLV NEQGHYDAVT GKFTCQVPGV YYFAVHATVY RASLQFDLVKNGESIASFFQ FFGGWPKPAS LSGGAMVRLE PEDQVWVQVG VGDYIGIYAS IKTDSTFSGF LVYSDWHSSP VFA.

Storage Instruction

Reconstituted store at -20°C or -80°C.We recommend that single use aliquots are prepared to avoid freeze-thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution

References

Not Available

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C1QTNF5

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