BSG

Alternative Names: Basigin isoform 2, CD147, EMMPRIN, Leukocyte activation antigen M6, OK blood group antigen, 5F7, OK, TCSF

Basigin Isoform 2 (BSG) is a type 1 transmembrane protein in the immunoglobulin superfamily. It undergoes N- and O-glycosylation and interacts with ligands like integrins, cyclophilin proteins Cyp-A and CyP-B. BSG plays a crucial role in intercellular recognition and various immunologic processes, as well as cell differentiation and development. It also regulates important cell processes like the expression of mono-carboxylate transporter and spermatogenesis. Moreover, Basigin Isoform 2 contributes to the invasion, metastasis, growth, and survival of malignant cells by releasing matrix metalloproteinases near mesenchymal cells and tumor cells.

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  • Sku: PSB-pro-2516-2µg
  • Vendor: ProSpec-Tany
$60.00 USD
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Title

Product Details

Product Description

Recombinant Human Basigin, also known as BSG or CD147, is a protein belonging to the immunoglobulin superfamily. With a molecular weight of approximately 45 kDa, this glycoprotein plays a significant role in various physiological and pathological processes. It is involved in cell adhesion, migration, and invasion, making it a crucial player in tumor progression and metastasis. Additionally, Recombinant Human Basigin is implicated in the regulation of immune responses, angiogenesis, and spermatogenesis, highlighting its diverse functions in different biological contexts.

Current Lead Time

7-14 Days

Product Specifications

Species
Human
Expression System Sf9 - Baculovirus cells
Purity 90.0 % by SDS-PAGE
Activity
Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
47.5 kDa
Structure Dimer
Endotoxin Concentration
Not Available
Purification Method Not Available
Form
Frozen
Formulation BSG protein solution (0.5mg/ml) contains phosphate buffered saline (pH7.4) and 10% glycerol.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

ADPAAGTVFT TVEDLGSKIL LTCSLNDSAT EVTGHRWLKG GVVLKEDALP GQKTEFKVDS DDQWGEYSCV FLPEPMGTAN IQLHGPPRVK AVKSSEHINE GETAMLVCKS ESVPPVTDWA WYKITDSEDK ALMNGSESRF FVSSSQGRSE LHIENLNMEA DPGQYRCNGT SSKGSDQAIITLRVRSHLAL EPKSCDKTHT CPPCPAPELL GGPSVFLFPP KPKDTLMISR TPEVTCVVVD VSHEDPEVKF NWYVDGVEVH NAKTKPREEQ YNSTYRVVSV LTVLHQDWLN GKEYKCKVSN KALPAPIEKT ISKAKGQPRE PQVYTLPPSR DELTKNQVSL TCLVKGFYPS DIAVEWESNGQPENNYKTTP PVLDSDGSFF LYSKLTVDKS RWQQGNVFSC SVMHEALHNH YTQKSLSLSP GKHHHHHH.

Storage Instruction

Reconstituted store at -20°C or -80°C.We recommend that single use aliquots are prepared to avoid freeze-thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution

References

Not Available

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BSG

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