BRAK

Alternative Names: C-X-C motif chemokine 14, Small-inducible cytokine B14, Chemokine BRAK, Bolekine, NJAC, KS1, Kec, BMAC, MIP-2g, SCYB14, CXCL14, BRAK, MGC10687.

CXCL14 is a cytokine that is involved in regulating the immune system and causing inflammation. It belongs to the same family as BRAK protein, which is also a member of the CXC cytokine subfamily. CXCL14 specifically attracts monocytes, but not lymphocytes, dendritic cells, neutrophils, or macrophages. It plays a role in maintaining the balance of monocyte-derived macrophages in the body.

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  • Sku: PSB-chm-001-5µg
  • Vendor: ProSpec-Tany
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Title

Product Details

Product Description

Recombinant Human BRAK (CXCL14) is a chemokine protein belonging to the CXC subfamily. With a molecular weight of approximately 8.4 kDa, this protein plays a role in immune response regulation and inflammation. Recombinant Human BRAK is commonly used in research settings to study its effects on cell migration, angiogenesis, and tumor growth. Its unique properties make it a valuable tool for investigating the intricate mechanisms of chemokine signaling pathways.

Current Lead Time

7-14 Days

Product Specifications

Species
Human
Expression System E. coli
Purity 95% by SDS-PAGE
Activity
The ED50 of CXCL14 as determined by its ability to induce calcium flux of prostaglandin E2 treated THP1 human acute monocytic leukemia cells was 1.0-10.0 ng/ml. The ED50 of CXCL14 as determined by its ability to induce calcium flux of prostaglandin E2 treated THP1 human acute monocytic leukemia cells was 1.0-10.0 ng/ml.
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
N/A
Structure Homodimer
Endotoxin Concentration
Not Available
Purification Method Not Available
Form
Lyophilized
Formulation CXCL14 was lyophilized after extensive dialysis against 20mM Tris-HCl, pH 8.5 and 1M NaCl.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

The sequence of the first five N-terminal amino acids was determined and was found to be Ser-Lys-Cys-Lys-Cys.

Storage Instruction

Lyophilized CXCL14 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution CXCL14 should be stored at 4°C between 2-7 days and for future use below -18°C.Please prevent freeze-thaw cycles.

Sample Prep Instruction

It is recommended to reconstitute the lyophilized CXCL14 in sterile 18M-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

References

Not Available

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BRAK

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