BMPR1B

Alternative Names:

Bone Morphogenetic Protein Receptor Type-1B, Bone Morphogenetic Protein Receptor, Type IB, BMP Type-1B Receptor, BMPR-1B, ALK6, Serine/Threonine Receptor Kinase, CDw293 Antigen, CDw293, ALK-6, EC 2.7.11.30, EC 2.7.11.

Recombinant Human Bone Morphogenetic Protein Receptor-1B (BMPR-1B) is a transmembrane receptor belonging to the bone morphogenetic protein (BMP) receptor family. It plays a key role in mediating BMP signaling pathways involved in bone and cartilage development. BMPR-1B has a molecular weight of approximately 70 kDa and is essential for proper skeletal formation and maintenance. Its activation triggers a cascade of intracellular events leading to the regulation of gene expression and cellular differentiation.

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  • Sku: PSB-cyt-897-2µg
  • Vendor: ProSpec-Tany
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Title

Product Details

Product Description

Recombinant Human Bone Morphogenetic Protein Receptor-1B (BMPR-1B) is a transmembrane receptor belonging to the bone morphogenetic protein (BMP) receptor family. It plays a key role in mediating BMP signaling pathways involved in bone and cartilage development. BMPR-1B has a molecular weight of approximately 70 kDa and is essential for proper skeletal formation and maintenance. Its activation triggers a cascade of intracellular events leading to the regulation of gene expression and cellular differentiation.

Current Lead Time

7-14 Days

Product Specifications

Species
Human
Expression System E. coli
Purity 80.0% by SDS-PAGE
Activity
Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
15.1 kDa
Structure Dimer
Endotoxin Concentration
Not Available
Purification Method Not Available
Form
Frozen
Formulation BMPR1B protein solution (0.5mg/ml) containing Phosphate buffered saline (pH7.4), 20% glycerol, 1mM DTT and 0.1mM PMSF.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

MGSSHHHHHH SSGLVPRGSH MGSKKEDGES TAPTPRPKVL RCKCHHHCPE DSVNNICSTD GYCFTMIEED DSGLPVVTSG CLGLEGSDFQ CRDTPIPHQR RSIECCTERN ECNKDLHPTL PPLKNRDFVD GPIHHR.

Storage Instruction

Reconstituted store at -20°C or -80°C.We recommend that single use aliquots are prepared to avoid freeze-thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution

References

Not Available

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BMPR1B

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