bHistone

Alternative Names: Not Available

Histone is a highly basic protein found in the nuclei of eukaryotic cells. It plays a role in organizing DNA into nucleosomes. There are five main families of histones: H1/H5, H2A, H2B, H3, and H4. The core histones are H2A, H2B, H3, and H4, while H1/H5 are known as linker histones. Chromatin structure is influenced by posttranslational modifications of histones and the presence of different histone variants. Histones H3 and H4 undergo covalent modifications at multiple residues, which contribute to the histone code along with modifications to H2A and H2B.

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  • Sku: PSB-pro-2558-50µg
  • Vendor: ProSpec-Tany
$300.00 USD
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Title

Product Details

Product Description

Bovine histone refers to a protein found in the nuclei of bovine cells, specifically in the chromatin structure. Belonging to the histone family, it plays a significant role in DNA packaging and gene regulation. With a weight of approximately 11 kilodaltons, bovine histone is involved in the formation of nucleosomes, which are fundamental units of chromatin organization. Through its interactions with DNA, this protein contributes to the maintenance of genome stability and the modulation of gene expression. Understanding the properties and functions of bovine histone is crucial for comprehending the intricate mechanisms underlying genetic processes in bovine species.

Current Lead Time

7-14 Days

Product Specifications

Species
Cattle
Expression System Bovine tissues
Purity 80.0% by SDS-PAGE
Activity
Not Available
Activity Assay
Animal Component Free (ACF) No
Molecular Weight
N/A
Structure Monomer
Endotoxin Concentration
Not Available
Purification Method Not Available
Form
Frozen
Formulation Histone Bovine is supplied in 20mM HEPES buffer pH-7.6, 250mM NaCl and 20% glycerol.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Storage Instruction

Reconstituted store at -20°C or -80°C.We recommend that single use aliquots are prepared to avoid freeze-thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution

References

Not Available

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bHistone

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