bGH

Alternative Names: Bovine GH, Growth hormone, GH1, Bovine Somatotropin, BGH, rBGH, BST, rBST

GH is a hormone in the somatotropin/prolactin family that helps regulate growth. It, along with four other genes, is located on chromosome 17 at the growth hormone locus. These genes share a high degree of sequence identity due to gene duplications. Alternative splicing creates different isoforms of each gene, leading to diversity. GH is expressed in the pituitary but not in placental tissue, unlike the other genes in the locus. Mutations or deletions in the gene can result in growth hormone deficiency and short stature.

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  • Sku: PSB-cyt-636-20µg
  • Vendor: ProSpec-Tany
$60.00 USD
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Safety Data Sheet
UniProt Listing
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Product Details

Product Description

Recombinant Bovine Growth Hormone (rBGH) is a genetically engineered hormone that belongs to the family of peptide hormones. It is used to increase milk production in dairy cows by stimulating the growth of mammary tissue. rBGH has a molecular weight of approximately 22 kDa and is produced by inserting the gene responsible for its synthesis into bacteria or yeast cells for mass production. This hormone has been a subject of controversy due to concerns about its potential impact on human health and animal welfare.

Current Lead Time

7-14 Days

Product Specifications

Species
 Bovine
Expression System E. coli
Purity 98.0 % by SDS-PAGE
Activity
 The activity as determined by the PDFP13B9 cells stably transfected with rabbit GH receptors. Bovine GH is also capable of forming a 1:2 complex with the recombinant ovine growth hormone receptor extracellular domain (ECD). The activity as determined by the PDFP13B9 cells stably transfected with rabbit GH receptors. Bovine GH is also capable of forming a 1:2 complex with the recombinant ovine growth hormone receptor extracellular domain (ECD).
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
 N/A
Structure Homodimer
Endotoxin Concentration
 Not Available
Purification Method Not Available
Form
 Lyophilized
Formulation The Bovine Growth Hormone protein was lyophilized from a concentrated (1mg/ml) solution with 4.5mM NaHCO3 adjusted to pH 8-9.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

1 afpamslsgl fanavlraqh lhqlaadtfk efertyipeg qrysiqntqv

Storage Instruction

Lyophilized Bovine Growth Hormone although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution GH Bovine should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.

Sample Prep Instruction

It is recommended to reconstitute the lyophilized Bovine Growth Hormone in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

References

Not Available
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bGH
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