BDNF

Alternative Names: BDNF, Brain-Derived Neurotrophic Factor, MGC34632.

BDNF plays a crucial role in promoting the survival of neuronal populations in the central nervous system and its connected regions. It regulates synaptic transmission and plasticity in various CNS regions, influencing adaptive neuronal responses such as long-term potentiation, long-term depression, and short-term synaptic plasticity. Additionally, BDNF helps regulate intrinsic neuronal excitability.

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  • Sku: PSB-cyt-207-2µg
  • Vendor: ProSpec-Tany
$60.00 USD
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Title

Product Details

Product Description

Recombinant Human Brain-Derived Neurotrophic Factor (rhBDNF) is a protein that belongs to the neurotrophin family. It plays a key role in the growth, survival, and maintenance of neurons in the brain. With a molecular weight of approximately 27 kDa, rhBDNF is involved in various physiological processes, including synaptic plasticity and cognitive function. This recombinant protein is commonly used in research studies to investigate its effects on neuronal development and function.

Current Lead Time

7-14 Days

Product Specifications

Species
Human
Expression System E. coli
Purity 97.0% by SDS-PAGE
Activity
The ED50, as determined by the dose-dependent induction of C6 cells proliferation, is 1.3-2µg/ml.
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
N/A
Structure Dimer
Endotoxin Concentration
Not Available
Purification Method Not Available
Form
Lyophilized
Formulation The protein was lyophilized without any additives.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

MHSDPARRGE LSVCDSISEW VTAADKKTAV DMSGGTVTVL EKVPVSKGQL KQYFYETKCN PMGYTKEGCR GIDKRHWNSQ CRTTQSYVRA LTMDSKKRIG WRFIRIDTSC VCTLTIKRGR.

Storage Instruction

Lyophilized BDNF although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution BDNF should be stored at 4°C between 2-7 days and for future use below -18°C.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.

Sample Prep Instruction

It is recommended to reconstitute the lyophilized BDNF in sterile 18M-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

References

Not Available

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BDNF

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