BD5

Alternative Names: Defensin, beta 105, DEFB-5, DEFB5, DEFB105, DEFB105A, DEFB105B, BD-5, BD5, Beta-defensin 105, eta-defensin 5.

Defensins are cationic peptides that have a broad range of antimicrobial activity and play a key role in the innate immune system. Human beta-defensins BD-1 to BD-6 are expressed on leukocytes and epithelial surfaces. In addition to their antimicrobial properties, beta-defensins can attract immature dendritic cells and memory T cells. Beta-defensins contain a 6-cysteine motif with 3 intra-molecular disulfide bonds.

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  • Sku: PSB-cyt-804-5µg
  • Vendor: ProSpec-Tany
$60.00 USD
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Title

Product Details

Product Description

Recombinant Human Beta Defensin-5 is a member of the beta-defensin family, which is a group of small, cationic peptides that play a role in the innate immune response. This particular peptide has a molecular weight of approximately 4.5 kDa. Recombinant Human Beta Defensin-5 is known for its antimicrobial properties and is involved in the defense against various pathogens. Its small size and positive charge allow it to interact with negatively charged microbial membranes, disrupting their integrity and leading to cell death.

Current Lead Time

7-14 Days

Product Specifications

Species
Human
Expression System E. coli
Purity 95% by SDS-PAGE
Activity
Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
N/A
Structure Homodimer
Endotoxin Concentration
Not Available
Purification Method Not Available
Form
Lyophilized
Formulation Lyophilized from a 0.2µm filtered concentrated solution in PBS, pH 7.4.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

GLDFSQPFPS GEFAVCESCK LGRGKCRKEC LENEKPDGNC RLNFLCCRQR I.

Storage Instruction

Lyophilized Beta Defensin-5 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution BD5 should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.

Sample Prep Instruction

It is recommended to reconstitute the lyophilized Beta Defensin-5 in sterile 18M-cm H₂O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

References

Not Available

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BD5

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