bCollagen-VI

Alternative Names: Not Available

Collagen, an important part of the extracellular matrix, is a fibrous protein that gives tissues their strength and structure. It has been used in various medical, pharmaceutical, and consumer products for more than a century. While collagen and gelatin, which is derived from collagen, are readily available and inexpensive, they are often not highly purified and can cause inflammation in some users. There are also concerns about contamination with the agent responsible for mad cow disease and Creutzfeldt-Jakob Disease. Animal collagens undergo ongoing modifications in the extracellular space, leading to differences in extractability and physical characteristics. This makes collagens from different sources variable and difficult to analyze. Products containing animal-derived collagen can potentially induce dangerous inflammatory or immune responses in humans and carry the risk of viral or prion contamination. In contrast, recombinant collagens closely resemble natural collagen, reducing the risk of inflammation, immune response, and disease compared to collagen from animals.

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  • Sku: PSB-pro-2730-250µg
  • Vendor: ProSpec-Tany
$350.00 USD
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Safety Data Sheet
UniProt Listing
NCBI Link

Product Details

Product Description

Bovine Collagen-VI is a protein found in the extracellular matrix of bovine tissues, belonging to the collagen family. With a weight of approximately 400 kDa, it plays a significant role in maintaining tissue structure and integrity. Bovine Collagen-VI provides mechanical support and contributes to the organization and stability of various tissues, including skin, tendons, and cartilage. Its unique molecular structure and arrangement of triple helices make it an essential component for tissue strength and elasticity.

Current Lead Time

7-14 Days

Product Specifications

Species
 Bovine
Expression System Bovine placenta
Purity 90 by SDS-PAGE
Activity
 Not Available
Activity Assay
Animal Component Free (ACF) No
Molecular Weight
 N/A
Structure Homodimer
Endotoxin Concentration
 Not Available
Purification Method Not Available
Form
 Lyophilized
Formulation Collagen-VI was lyophilized without additives.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Storage Instruction

Lyophilized Collagen-VI although stable at room temperature for 3 weeks, should be stored desiccated below -18C. Upon reconstitution Collagen-VI should be stored at 4C between 2-7 days and for future use below -18C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.

Sample Prep Instruction

It is recommended to Add 0.5 M acetic acid, pH 2.5 to prepare a working stock solution not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

References

Not Available
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