bCollagen-II

Alternative Names: Not Available

Collagen is a fibrous protein found in the extracellular matrix that gives tissues their strength and structural integrity. It has been used in medical, pharmaceutical, and consumer products for over a century due to its abundant and inexpensive supply derived from animal remains. However, these materials are often impure and can cause inflammatory reactions in some users. There are also concerns about contamination with the agents that cause mad cow disease and Creutzfeldt-Jakob Disease. Animal collagens undergo modifications throughout their lifespan, leading to variability in extractability and biophysical characteristics. This makes them difficult to analyze. Products containing animal-derived collagen can induce harmful immune responses and pose a risk of viral or prion contamination. Recombinant collagens, on the other hand, are nearly identical to native collagen and offer reduced risks of inflammation, immune response, and disease compared to animal-sourced collagen.

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  • Sku: PSB-pro-2679-250µg
  • Vendor: ProSpec-Tany
$165.00 USD
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Safety Data Sheet
UniProt Listing
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Product Details

Product Description

Bovine Collagen-II is a protein derived from the cartilage of cows, specifically from the type II collagen family. With a molecular weight ranging from 100 to 300 kDa, it plays a significant role in maintaining the structural integrity and function of various connective tissues in the body. Bovine Collagen-II is widely recognized for its potential therapeutic applications due to its unique amino acid composition and triple-helical structure, which contribute to its stability and bioactivity. As a key component of cartilage, this collagen type is of interest in research and development efforts aimed at addressing joint health and related conditions.

Current Lead Time

7-14 Days

Product Specifications

Species
 Bovine
Expression System Bovine knee joint
Purity 95 by SDS-PAGE
Activity
 Not Available
Activity Assay
Animal Component Free (ACF) No
Molecular Weight
 N/A
Structure Monomer
Endotoxin Concentration
 Not Available
Purification Method Not Available
Form
 Lyophilized
Formulation Collagen-II was lyophilized without additives.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Storage Instruction

Lyophilized Collagen-II although stable at room temperature for 3 weeks, should be stored desiccated below -18C. Upon reconstitution Collagen-II should be stored at 4C between 2-7 days and for future use below -18C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.

Sample Prep Instruction

It is recommended to Add 50 mM acetic acid to prepare a working stock solution of approximately 1-5mg/ml and let the lyophilized pellet dissolve completely.

References

Not Available
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bCollagen-II
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