BCL7A

Alternative Names: BCL7A, BCL7, B-cell CLL/lymphoma 7 protein family member A

B-cell CLL/lymphoma 7A (BCL7A) is a member of the BCL7 family and is directly involved in gene translocation in Burkitt lymphoma. The disruption of the N-terminal region of the BCL7A gene through this translocation is thought to be connected to the pathogenesis of a specific type of high-grade B cell non-Hodgkin lymphoma. This N-terminal portion shares a sequence similarity with BCL7B and BCL7C. Abnormalities in BCL7A may contribute to the development of B-cell non-Hodgkin lymphoma.

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  • Sku: PSB-pro-1318-2µg
  • Vendor: ProSpec-Tany
$60.00 USD
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Title

Product Details

Product Description

Recombinant Human B-cell CLL/lymphoma 7A, commonly referred to as BCL7A, is a protein belonging to the B-cell CLL/lymphoma 7 (BCL7) family. With a molecular weight of approximately X kilodaltons, BCL7A plays a significant role in various cellular processes. Its involvement in gene regulation, cell cycle progression, and tumorigenesis make it an intriguing target for scientific research. Understanding the functional mechanisms and interactions of BCL7A can provide valuable insights into the pathogenesis of certain diseases, including lymphomas and leukemias.

Current Lead Time

7-14 Days

Product Specifications

Species
Human
Expression System E. coli
Purity 85.0% by SDS-PAGE
Activity
Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
25.2 kDa
Structure Dimer
Endotoxin Concentration
Not Available
Purification Method Not Available
Form
Frozen
Formulation BCL7A protein solution (0.25mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 0.15M NaCl, 10% glycerol, 1mM DTT and 2mM EDTA.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

MGSSHHHHHH SSGLVPRGSH MGSMSGRSVR AETRSRAKDD IKRVMAAIEK VRKWEKKWVT VGDTSLRIYK WVPVTEPKVD DKNKNKKKGK DEKCGSEVTT PENSSSPGMM DMHDDNSNQS SIADASPIKQ ENSSNSSPAP EPNSAVPSDG TEAKVDEAQA DGKEHPGAED ASDEQNSQSS MEHSMNSSEK VDRQPSGDSG LAAETSAISQ DLEGVPPSKK MKLEASQQNS EEM.

Storage Instruction

Reconstituted store at -20°C or -80°C.We recommend that single use aliquots are prepared to avoid freeze-thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution

References

Not Available

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BCL7A

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