BCL2L2, His

Alternative Names: B-Cell Lymphoma Protein 2, BCL2 Like 2, BCL2L2, BCL-W, BCLW, Bcl2-L-2, Apoptosis regulator Bcl-W, BCL2 Like protein 2, KIAA0271.

BCL2L2 promotes cell survival and prevents dexamethasone-induced cell death by inhibiting the death-promoting effects of BAX. This protein is a member of the BCL-2 protein family, which regulates cell apoptosis. BCL2L2 reduces cell death in toxic conditions and is crucial for the survival of NGF- and BDNF-dependent neurons. Additionally, BCL2L2 is significant in adult spermatogenesis.

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  • Sku: PSB-pro-768-5µg
  • Vendor: ProSpec-Tany
$60.00 USD
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Title

Product Details

Product Description

Recombinant Human BCL2 Like 2, His Tag is a protein that belongs to the BCL2 family, which plays a significant role in regulating apoptosis (programmed cell death). This protein is expressed in various tissues and is involved in maintaining cellular homeostasis by inhibiting apoptosis. With a molecular weight of approximately X kDa, Recombinant Human BCL2 Like 2, His Tag is a valuable tool for studying the intricate mechanisms underlying cell survival and death pathways.

Current Lead Time

7-14 Days

Product Specifications

Species
Human
Expression System E. coli
Purity 95% by SDS-PAGE
Activity
Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
N/A
Structure Homodimer
Endotoxin Concentration
Not Available
Purification Method Not Available
Form
Frozen
Formulation The BCL2L2 protein solution contains 20mM Tris-HCl, pH-8, 100mM NaCl and 10% glycerol.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

MGSSHHHHHH SSGLVPRGSH MATPASAPDT RALVADFVGY KLRQKGYVCG AGPGEGPAAD PLHQAMRAAG DEFETRFRRT FSDLAAQLHV TPGSAQQRFT QVSDELFQGG PNWGRLVAFF VFGAALCAES VNKEMEPLVG QVQEWMVAYL ETRLADWIHS SGGWAEFTAL YGDGALEEAR RLREGNWASV RT.

Storage Instruction

Reconstituted store at -20°C or -80°C.We recommend that single use aliquots are prepared to avoid freeze-thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution

References

Not Available

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BCL2L2, His

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