Bcl-XL His

Alternative Names: Bcl-XL, Bcl-X(L), BclXL

Bcl-XL, a transmembrane protein found in the mitochondrial membranes of long-lived and postmitotic cells like adult brain cells, plays a role in the signal transduction pathway of FAS-Ligand. As a member of the Bcl-2 protein family, Bcl-XL is an anti-apoptotic protein that forms heterodimers, an important process in the regulation of cell death. Bcl-XL is also involved in promoting cell survival, including in cancer cells. In summary, Bcl-XL is a critical regulator of apoptosis and acts as a survival protein.

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  • Sku: PSB-pro-641-2µg
  • Vendor: ProSpec-Tany
$60.00 USD
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Safety Data Sheet
UniProt Listing
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Product Details

Product Description

Recombinant Human B-Cell Leukemia/Lymphoma His Tag is a protein that belongs to the B-cell leukemia/lymphoma family. With a weight of approximately X kDa, this protein plays a significant role in various cellular processes. Its His tag allows for efficient purification and detection in laboratory settings. Understanding the properties and functions of Recombinant Human B-Cell Leukemia/Lymphoma His Tag is crucial for investigating its involvement in disease mechanisms and potential therapeutic applications.

Current Lead Time

7-14 Days

Product Specifications

Species
 Human
Expression System E. coli
Purity 95% by SDS-PAGE
Activity
 Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
 N/A
Structure Homodimer
Endotoxin Concentration
 Not Available
Purification Method Not Available
Form
 Lyophilized
Formulation The protein contains 10mM Tris-HCL pH-8, 1mM EDTA and 250mM NaCl.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Storage Instruction

Lyophilized Bcl-XL although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Bcl-XL should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.

Sample Prep Instruction

Suspend BclXL in 100?l of 0.5M Acetic acid, over night at 4°C. Dilute 10 fold into selected buffer system. Bcl-XL has tendency to form intramolecular disulfide bond, 5mM DTT is recommended in assay buffer. When running SDS-PAGE gel, 10mM DTT is recommended.

References

Not Available
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Bcl-XL His
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