Bcl-XL GST

Alternative Names: Bcl-XL, Bcl-X(L), BclXL

Bcl-XL, a transmembrane protein found in the mitochondria of long-lived and postmitotic cells like adult brain cells, plays a role in the FAS-Ligand signal transduction pathway. As a member of the Bcl-2 family, it has anti-apoptotic properties and is involved in the regulation of apoptosis through the formation of heterodimers. Bcl-XL is also important for the survival of cancer cells, acting as the main regulator of active cell suicide. Its cell death repressor activity makes it a survival protein.

Skip to product information
  • Sku: PSB-pro-640-2µg
  • Vendor: ProSpec-Tany
$60.00 USD
 per 
Shipping calculated at checkout.

Contact us directly for international purchases.

Title

Product Details

Product Description

Recombinant Human B-Cell Leukemia/Lymphoma XL GST Tag is a protein that belongs to the GST (Glutathione S-transferase) family. With a weight of approximately X kilodaltons, this protein plays a significant role in various cellular processes. It exhibits enzymatic activity, facilitating the conjugation of reduced glutathione to a wide range of electrophilic substrates. The Recombinant Human B-Cell Leukemia/Lymphoma XL GST Tag is commonly utilized in research and biotechnological applications due to its ability to be easily purified using glutathione affinity chromatography.

Current Lead Time

7-14 Days

Product Specifications

Species
Human
Expression System E. coli
Purity 95% by SDS-PAGE
Activity
Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
N/A
Structure Monomer
Endotoxin Concentration
Not Available
Purification Method Not Available
Form
Lyophilized
Formulation The protein contains 10mM Tris-HCL pH-8, 1mM EDTA and 250mM NaCl.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Storage Instruction

Lyophilized Bcl-XL although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Bcl-XL should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.

Sample Prep Instruction

Suspend BclXL in 100?l of 0.5M Acetic acid, over night at 4°C. Dilute 10 fold into selected buffer system. Bcl-XL has tendency to form intramolecular disulfide bond, 5mM DTT is recommended in assay buffer. When running SDS-PAGE gel, 10mM DTT is recommended.

References

Not Available

View full details

Bcl-XL GST

SUBHEADING

Recently viewed products