Bcl-XL

Alternative Names: Bcl-XL, Bcl-X(L), BclXL

Bcl-XL, a transmembrane protein found in the mitochondrial membranes of long-lived and postmitotic cells like adult brain cells, plays a role in the FAS-Ligand signal transduction pathway. It is an anti-apoptotic protein belonging to the Bcl-2 family, and forms heterodimers which regulate apoptosis. Bcl-XL is critical for the survival of cancer cells as it acts as a survival protein and represses cell death.

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  • Sku: PSB-pro-639-10µg
  • Vendor: ProSpec-Tany
$60.00 USD
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Title

Product Details

Product Description

Recombinant Human B-Cell Leukemia/Lymphoma XL is a protein-based therapeutic agent that belongs to the family of recombinant human proteins. With a weight of [insert weight], this pharmaceutical substance is specifically designed to target and treat B-cell leukemia and lymphoma, two types of blood cancers affecting the B-cells of the immune system. By leveraging its molecular structure, Recombinant Human B-Cell Leukemia/Lymphoma XL aims to provide a targeted therapeutic approach for patients diagnosed with these conditions.

Current Lead Time

7-14 Days

Product Specifications

Species
Human
Expression System E. coli
Purity 95% by SDS-PAGE
Activity
Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
N/A
Structure Homodimer
Endotoxin Concentration
Not Available
Purification Method Not Available
Form
Lyophilized
Formulation The protein contains 10mM Tris-HCl pH-8, 1mM EDTA and 250mM NaCl.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Storage Instruction

Lyophilized Bcl-XL although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Bcl-XL should be stored at 4°C between 2-7 days and for future use below -18°C.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.

Sample Prep Instruction

Suspend BclXL in 1000µl sterile 18M-cm H2O, over night at 4°C. Dilute 10 fold into selected buffer system.Bcl-XL has tendency to form intramolecular disulfide bond, 5mM DTT is recommended in assay buffer. When running SDS-PAGE gel, 10mM DTT is recommended.

References

Not Available

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Bcl-XL

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