Product Description

Recombinant Human B-Cell Leukemia/Lymphoma 2 -NWGR is a protein that belongs to the Bcl-2 family, a group of proteins involved in regulating cell apoptosis (programmed cell death) and maintaining cellular homeostasis. With a molecular weight of approximately X kDa, this protein plays a role in inhibiting apoptosis by preventing the release of cytochrome c from the mitochondria, thus blocking the activation of caspases. It is involved in various cellular processes, including cell survival, differentiation, and proliferation, making it a subject of interest in cancer research and therapeutic development.

Current Lead Time

7-14 Days

Product Specifications

*For Research Use Only

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

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Lyophilized Bcl-2 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Bcl-2 should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.

Suspend Bcl-2 in 100?l of 0.5M Acetic acid, over night at 4°C. Dilute 10 fold into selected buffer system. BCL-2 has tendency to form intramolecular disulfide bond, 5mM DTT is recommended in assay buffer. When running SDS-PAGE gel, 10mM DTT is recommended.

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