BAD

Alternative Names: Bcl2 antagonist of cell death, BAD, Bcl-2-binding component 6, Bcl-XL/Bcl-2-associated death promoter, Bcl-2-like 8 protein, BAD Protein, BBC6, BCL2L8.

The Bcl-2 family is a group of proteins that can regulate cell death in many different situations. Some proteins in this family, like Bcl-2, prevent cell death, while others, like Bax and Bak, promote cell death. Bad is similar to Bcl-2 in one part of its structure, but not to other related proteins. In mammalian cells, Bad binds more tightly to Bcl-xL than to Bcl-2, and it can counteract the ability of Bcl-xL to prevent cell death, but not the ability of Bcl-2.

Skip to product information
  • Sku: PSB-pro-458-2µg
  • Vendor: ProSpec-Tany
$175.00 USD
 per 
Shipping calculated at checkout.

Contact us directly for international purchases.

Title

Product Details

Product Description

Recombinant Human BAD, a member of the Bcl-2 protein family, is a protein of interest in various scientific research applications. With a molecular weight of approximately X kDa, it plays a role in apoptosis regulation and cell survival pathways. This recombinant protein is derived from human sources and is commonly used in studies investigating cellular signaling, cancer research, and therapeutic development. Its significance lies in its involvement in the intricate mechanisms governing cell fate, making it a valuable tool for understanding and potentially manipulating cellular processes.

Current Lead Time

7-14 Days

Product Specifications

Species
Human
Expression System E. coli
Purity
Activity
Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
N/A
Structure Homodimer
Endotoxin Concentration
Not Available
Purification Method Not Available
Form
Frozen
Formulation BAD protein in 50mM Tris-Acetate, pH7.5, 1mM EDTA, 20% Glycerol.

*For Research Use Only

Notes

Applications: • ELISA • Western Blotting

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

Check Uniprot Link

Storage Instruction

Reconstituted store at -20°C or -80°C.We recommend that single use aliquots are prepared to avoid freeze-thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution

References

Not Available

View full details

BAD

SUBHEADING

Recently viewed products