BAALC

Alternative Names: FLJ12015, Brain and acute leukemia cytoplasmic protein, BAALC.

The BAALC gene is present in patients with acute myeloid leukemia and is conserved in mammals but not lower organisms. BAALC is expressed in tissues derived from the neuroectoderm and is found in both cell membranes and cytoplasm. There are multiple variations of BAALC due to alternative splicing. It is expressed in hematopoetic and neural cells and interacts with CaMKII?, playing a role in synaptic function at postsynaptic lipid rafts. Overexpression of BAALC is associated with a poor clinical outcome and is a significant risk factor for cytogenetically normal acute myeloid leukemia (AML).

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  • Sku: PSB-pro-758-2µg
  • Vendor: ProSpec-Tany
$60.00 USD
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Title

Product Details

Product Description

Recombinant Human Brain and Acute Leukemia, Cytoplasmatic is a protein belonging to the family of cytoplasmatic proteins. With a weight of [insert weight], this protein plays a significant role in the pathogenesis and progression of acute leukemia, particularly in the brain. It is involved in various cellular processes, including signal transduction, cell cycle regulation, and apoptosis. Understanding the molecular mechanisms underlying this protein's function can provide valuable insights into the development of targeted therapies for acute leukemia, making it a subject of scientific interest and investigation.

Current Lead Time

7-14 Days

Product Specifications

Species
Human
Expression System E. coli
Purity 95% by SDS-PAGE
Activity
Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
N/A
Structure Dimer
Endotoxin Concentration
Not Available
Purification Method Not Available
Form
Frozen
Formulation The protein solution contains 20mM Tris buffer pH-8, 1mM DTT, 20% glycerol and 2mM EDTA.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

MGSSHHHHHH SSGLVPRGSH MGCGGSRADA IEPRYYESWT RETESTWLTY TDSDAPPSAA APDSGPEAGG LHSGMLEDGL PSNGVPRSTA PGGIPNPEKK TNCETQCPNP QSLSSGPLTQ KQNGLQTTEA KRDAKRMPAK EVTINVTDSI QQMDRSRRIT KNCVN.

Storage Instruction

Reconstituted store at -20°C or -80°C.We recommend that single use aliquots are prepared to avoid freeze-thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution

References

Not Available

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BAALC

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