B3GAT3

Alternative Names: GLCATI, Glucuronosyltransferase I, GlcAT-I, GlcUAT-I, Beta-1,3-glucuronyltransferase 3, B3GAT3, Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3, UDP-GlcUA:Gal beta-1,3-Gal-R glucuronyltransferase.

B3GAT3 plays a key role in the synthesis of the tetrasaccharide found in heparan sulfate and chondroitin sulfate, as well as the l2/HNK-1 carbohydrate epitope on glycoproteins. It specifically targets Gal-beta-1,3-Gal-beta-1,4-Xyl without incorporating into other galactoside substrates like Galbeta1-3Gal beta1-O-benzyl, Galbeta1-4GlcNAc, and Galbeta1-4Glc.

  •
  • Sku: PSB-enz-711-5µg
  • Vendor: ProSpec-Tany
$60.00 USD
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UniProt Listing
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Product Details

Product Description

Recombinant Human Beta-1,3-Glucuronyltransferase 3 is an enzyme that belongs to the glycosyltransferase family. It plays a crucial role in the biosynthesis of glycosaminoglycans, specifically in the addition of glucuronic acid to the growing polysaccharide chain. This enzyme has a molecular weight of approximately 40 kDa. Recombinant Human Beta-1,3-Glucuronyltransferase 3 is commonly used in research and biotechnology applications for its ability to modify carbohydrate structures.

Current Lead Time

7-14 Days

Product Specifications

Species
 Human
Expression System E. coli
Purity 90% by SDS-PAGE
Activity
 Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
 36.4 kDa
Structure Homodimer
Endotoxin Concentration
 Not Available
Purification Method Not Available
Form
 Frozen
Formulation B3GAT3 protein solution (1mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 0.15M NaCl, 10% glycerol and 1mM DTT.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

MGSSHHHHHH SSGLVPRGSH MGSQPCDCLP PLRAAAEQLR QKDLRISQLQ AELRRPPPAP AQPPEPEALP TIYVVTPTYA RLVQKAELVR LSQTLSLVPR LHWLLVEDAE GPTPLVSGLL AASGLLFTHL VVLTPKAQRL REGEPGWVHP RGVEQRNKAL DWLRGRGGAV GGEKDPPPPG TQGVVYFADD DNTYSRELFE EMRWTRGVSV WPVGLVGGLR FEGPQVQDGR VVGFHTAWEP SRPFPVDMAG FAVALPLLLD KPNAQFDSTA PRGHLESSLL SHLVDPKDLE PRAANCTRVL VWHTRTEKPK MKQEEQLQRQ GRGSDPAIEV.

Storage Instruction

Reconstituted store at -20°C or -80°C.We recommend that single use aliquots are prepared to avoid freeze-thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution
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References

Not Available
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B3GAT3
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