B2M His

Alternative Names: Beta-2-microglobin, Beta chain of MHC class I molecules, Beta 2 Microglobulin, B2M.

B2M, a member of the MHC class I family, aids in presenting peptide antigens to the immune system. It is found on the surface of various cells, particularly white blood cells. Elevated levels of B2M in the blood are seen when there is increased production or destruction of these cells. This rise is particularly notable in individuals recently diagnosed with multiple myeloma, a type of cancer that involves white blood cells. B2M testing is primarily used to assess individuals for certain cancers affecting white blood cells (such as chronic lymphocytic leukemia, non-Hodgkin's lymphoma, and multiple myeloma) or kidney disease.

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  • Sku: PSB-pro-859-1µg
  • Vendor: ProSpec-Tany
$60.00 USD
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Title

Product Details

Product Description

Recombinant Human Beta 2 Microglobulin, His Tag is a protein that belongs to the beta-2 microglobulin family. With a molecular weight of approximately 12.5 kDa, this protein plays a significant role in the immune system by forming a complex with major histocompatibility complex class I molecules. It is involved in antigen presentation and immune response regulation. The His tag allows for easy purification and detection of the protein. This recombinant protein is commonly used in research and diagnostic applications due to its stability and consistent performance.

Current Lead Time

7-14 Days

Product Specifications

Species
Human
Expression System E. coli
Purity 95% by SDS-PAGE
Activity
Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
N/A
Structure Monomer
Endotoxin Concentration
Not Available
Purification Method Not Available
Form
Frozen
Formulation B2M Human solution containing 20mM Tris pH-8, 2mM DTT, 0.1M NaCl & 20% glycerol.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

MGSSHHHHHH SSGLVPRGSH MIQRTPKIQV YSRHPAENGK SNFLNCYVSG FHPSDIEVDL LKNGERIEKV EHSDLSFSKD WSFYLLYYTE FTPTEKDEYA CRVNHVTLSQ PKIVKWDRDM.

Storage Instruction

Reconstituted store at -20°C or -80°C.We recommend that single use aliquots are prepared to avoid freeze-thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution

References

Not Available

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B2M His

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