ASNA1

Alternative Names: EC 3.6.-.-, EC 3.6.3.16, Arsenite-Stimulated ATPase, Arsenite Transporter ATP-Binding Homolog 1 (Bacterial), Arsenical Pump-Driving ATPase, Arsenite-Stimulated ATPase, Arsenite-Stimulated ATPase, Arsenite Transporter ATP-Binding Homolog 1 (Bacterial), Arsenical Pump-Driving ATPase, ASNA-I, ATPase ASNA1, ARSA-I, GET3, Golgi To ER Traffic 3 Homolog, Transmembrane Domain Recognition Complex 40 KDa ATPase Subunit, Transmembrane Domain Recognition Complex 40kDa, TRC40, HASNA-I, HARSA-I, ARSA, ARSA1.

ASNA1, also known as Arsenite Transporter, ATP-Binding, Homolog 1, belongs to the arsA ATPase family and serves as the human counterpart of the bacterial arsA gene. In E.coli, the arsA ATPase functions as the catalytic unit of a multi-unit oxyanion pump responsible for resistance against arsenicals and antimonials. ASNA1 plays a crucial role as a major component of the transmembrane domain (TMD) recognition complex (TRC), which facilitates the post-translational delivery of tail-anchored (TA) proteins from the cytosol to the endoplasmic reticulum (ER).

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  • Sku: PSB-pro-1247-5µg
  • Vendor: ProSpec-Tany
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Safety Data Sheet
UniProt Listing
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Product Details

Product Description

Recombinant Human arsA Arsenite Transporter, ATP-Binding, Homolog 1 is a protein that plays a vital role in the transport of arsenite across cellular membranes. It belongs to the ATP-binding cassette (ABC) transporter family, which is involved in the active transport of various molecules across cell membranes. With a molecular weight of approximately X kDa, this protein is crucial for maintaining cellular homeostasis by facilitating the efflux of toxic arsenic compounds. Its functional significance in arsenic detoxification makes it a subject of interest in environmental and biomedical research.

Current Lead Time

7-14 Days

Product Specifications

Species
 Human
Expression System E. coli
Purity 90% by SDS-PAGE
Activity
 Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
 N/A
Structure Homodimer
Endotoxin Concentration
 Not Available
Purification Method Not Available
Form
 Frozen
Formulation The ASNA1 solution (1mg/1ml) contains 20mM Tris-HCl buffer (pH 8.0) and 10% glycerol.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

MGSSHHHHHH SSGLVPRGSH MGSMAAGVAG WGVEAEEFED APDVEPLEPT LSNIIEQRSL KWIFVGGKGG VGKTTCSCSL AVQLSKGRES VLIISTDPAH NISDAFDQKF SKVPTKVKGY DNLFAMEIDP SLGVAELPDE FFEEDNMLSM GKKMMQEAMS AFPGIDEAMS YAEVMRLVKG MNFSVVVFDT APTGHTLRLL NFPTIVERGL GRLMQIKNQI SPFISQMCNM LGLGDMNADQ LASKLEETLP VIRSVSEQFK DPEQTTFICV CIAEFLSLYE TERLIQELAK CKIDTHNIIV NQLVFPDPEK PCKMCEARHK IQAKYLDQME DLYEDFHIVK LPLLPHEVRG ADKVNTFSAL LLEPYKPPSA Q.

Storage Instruction

Reconstituted store at -20°C or -80°C.We recommend that single use aliquots are prepared to avoid freeze-thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution
​

References

Not Available
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ASNA1
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