ARSG

Alternative Names: Arylsulfatase G, ASG, ARSG, KIAA1001, UNQ839/PRO1777

Arylsulfatase G (ARSG) is a lysosomal enzyme that belongs to the sulfatase family. Sulfatases catalyze the hydrolysis of sulfate esters from various compounds such as steroids, carbohydrates, proteoglycans, and glycolipids. They play a role in hormone biosynthesis, cell signaling, and degradation of macromolecules. ARSG exhibits its arylsulfatase activity in acidic pH conditions, typical of lysosomal enzymes. It is inhibited by phosphate, which forms a covalent bond with the active site 3-oxoalanine. ARSG is found in lysosomes and is widely expressed, with low levels in the brain, lung, heart, and skeletal muscle.

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  • Sku: PSB-enz-677-5µg
  • Vendor: ProSpec-Tany
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Title

Product Details

Product Description

Recombinant Human Arylsulfatase G is an enzyme belonging to the arylsulfatase family, specifically designed for use in research and biotechnological applications. With a molecular weight of approximately 70 kDa, this enzyme plays a key role in the hydrolysis of sulfate esters in various biological processes. Recombinant Human Arylsulfatase G is commonly utilized in the study of sulfatase deficiencies and related disorders, making it a valuable tool for investigating the mechanisms underlying these conditions.

Current Lead Time

7-14 Days

Product Specifications

Species
Human
Expression System E. coli
Purity 85 % by SDS-PAGE
Activity
Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
N/A
Structure Homodimer
Endotoxin Concentration
Not Available
Purification Method Not Available
Form
Frozen
Formulation The ARSG solution (1mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 0.4M Urea and 10% glycerol.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

MGSSHHHHHH SSGLVPRGSH MGSGFLYPLV DFCISGKTRG QKPNFVIILA DDMGWGDLGA NWAETKDTAN LDKMASEGMR FVDFHAAAST CSPSRASLLT GRLGLRNGVT RNFAVTSVGG LPLNETTLAE VLQQAGYVTG IIGKWHLGHH GSYHPNFRGF DYYFGIPYSH DMGCTDTPGY NHPPCPACPQ GDGPSRNLQR DCYTDVALPL YENLNIVEQP VNLSSLAQKY AEKATQFIQR ASTSGRPFLL YVALAHMHVP LPVTQLPAAP RGRSLYGAGL WEMDSLVGQI KDKVDHTVKE NTFLWFTGDN GPWAQKCELA GSVGPFTGFW QTRQGGSPAK QTTWEGGHRV PALAYWPGRV PVNVTSTALL SVLDIFPTVV ALAQASLPQG RRFDGVDVSE VLFGRSQPGH RVLFHPNSGA AGEFGALQTV RLERYKAFYI TGGARACDGS TGPELQHKFP LIFNLEDDTA EAVPLERGGA EYQAVLPEVR KVLADVLQDI ANDNISSADY TQDPSVTPCC NPYQIACRCQ AA.

Storage Instruction

Reconstituted store at -20°C or -80°C.We recommend that single use aliquots are prepared to avoid freeze-thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution

References

Not Available

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ARSG

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