ARL4D

Alternative Names: ADP-ribosylation factor-like protein 4L, ADP-ribosylation factor-like 4D, ARL6, ARF4L.

ARL4D is a regulated member of the ARF/ARL family of GTPases. It switches between inactive and active forms and is regulated by GEF and GAP. ARL4D is involved in cellular trafficking. Mutations in this gene are associated with Bardet-Biedl syndrome.

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  • Sku: PSB-pro-953-5µg
  • Vendor: ProSpec-Tany
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Title

Product Details

Product Description

Recombinant Human ADP-Ribosylation Factor-Like 4D (ARL4D) is a protein that belongs to the ADP-ribosylation factor (ARF) family. With a molecular weight of approximately 20 kDa, ARL4D plays a role in intracellular vesicle trafficking and cytoskeletal organization. It functions as a molecular switch by cycling between an inactive GDP-bound form and an active GTP-bound form, thereby regulating various cellular processes. ARL4D's involvement in these fundamental cellular mechanisms highlights its significance in maintaining cellular homeostasis and underscores its potential as a target for therapeutic interventions.

Current Lead Time

7-14 Days

Product Specifications

Species
Human
Expression System E. coli
Purity 90% by SDS-PAGE
Activity
Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
N/A
Structure Homodimer
Endotoxin Concentration
Not Available
Purification Method Not Available
Form
Frozen
Formulation The ARL4D solution (0.25mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 2mM DTT, 0.2M NaCl and 20% glycerol.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

MGSSHHHHHH SSGLVPRGSH MGNHLTEMAP TASSFLPHFQ ALHVVVIGLD SAGKTSLLYR LKFKEFVQSV PTKGFNTEKI RVPLGGSRGI TFQVWDVGGQ EKLRPLWRSY TRRTDGLVFV VDAAEAERLE EAKVELHRIS RASDNQGVPV LVLANKQDQP GALSAAEVEK RLAVRELAAA TLTHVQGCSA VDGLGLQQGL ERLYEMILKR KKAARGGKKR R

Storage Instruction

Reconstituted store at -20°C or -80°C.We recommend that single use aliquots are prepared to avoid freeze-thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution

References

Not Available

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ARL4D

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