ARL4A

Alternative Names: ARL4A, ADP-ribosylation factor-like protein 4A

ARL4A, a member of the ARF-like protein subfamily of small GTPases, has close association with ARL6 and ARL7. Unlike ARFs, ARL4 does not activate the cholera toxin ADP-ribosyltransferase. ARL4A plays a role in neurogenesis during embryonic development and somitogenesis in early adult spermatogenesis.

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  • Sku: PSB-pro-895-2µg
  • Vendor: ProSpec-Tany
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Title

Product Details

Product Description

Recombinant Human ADP-Ribosylation Factor-Like 4A (ARL4A) is a protein belonging to the ADP-ribosylation factor (ARF) family. With a molecular weight of approximately 21 kDa, ARL4A plays a role in intracellular vesicular trafficking and membrane dynamics. It functions as a molecular switch, cycling between an inactive GDP-bound state and an active GTP-bound state, thereby regulating various cellular processes. ARL4A is involved in the regulation of Golgi apparatus organization, endocytic recycling, and cytoskeletal rearrangement. Understanding the functional significance of ARL4A can provide valuable insights into cellular processes and potential therapeutic targets.

Current Lead Time

7-14 Days

Product Specifications

Species
Human
Expression System E. coli
Purity 90% by SDS-PAGE
Activity
Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
N/A
Structure Monomer
Endotoxin Concentration
Not Available
Purification Method Not Available
Form
Frozen
Formulation The ARL4A solution (1mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 1mM DTT, 0.1M NaCl and 20% glycerol.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

MGSSHHHHHH SSGLVPRGSH MGNGLSDQTS ILSNLPSFQS FHIVILGLDC AGKTTVLYRL QFNEFVNTVP TKGFNTEKIK VTLGNSKTVT FHFWDVGGQE KLRPLWKSYT RCTDGIVFVV DSVDVERMEE AKTELHKITR ISENQGVPVL IVANKQDLRN SLSLSEIEKL LAMGELSSST PWHLQPTCAI IGDGLKEGLE KLHDMIIKRR KMLRQQKKKR

Storage Instruction

Reconstituted store at -20°C or -80°C.We recommend that single use aliquots are prepared to avoid freeze-thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution

References

Not Available

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ARL4A

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