ARL3

Alternative Names: ARFL3, ARL3, ADP-ribosylation factor-like protein 3

ARL3 is a small GTPase belonging to the ARL subfamily. Unlike ARFs, ARL3 does not activate the cholera toxin ADP-ribosyltransferase. ARL3 is found throughout the body. It likely plays a role in maintaining rod photoreceptor cells and regulating processes dependent on microtubules. Knocking down ARL3 results in changes in cell shape, difficulties in cell division, increased acetylation of alpha tubulin, and an increase in cells with two nuclei.

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  • Sku: PSB-pro-939-5µg
  • Vendor: ProSpec-Tany
$60.00 USD
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Title

Product Details

Product Description

Recombinant Human ADP-Ribosylation Factor-Like 3 (ARL3) is a protein that belongs to the ADP-ribosylation factor (ARF) family. With a molecular weight of approximately X kilodaltons, ARL3 plays a significant role in intracellular vesicular trafficking and membrane dynamics. It is involved in the regulation of ciliary function and has been implicated in various cellular processes, including protein trafficking, cell division, and signal transduction. This recombinant protein is commonly used in research studies to investigate the functional mechanisms and interactions of ARL3 within cellular pathways.

Current Lead Time

7-14 Days

Product Specifications

Species
Human
Expression System E. coli
Purity 95% by SDS-PAGE
Activity
Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
N/A
Structure Dimer
Endotoxin Concentration
Not Available
Purification Method Not Available
Form
Frozen
Formulation ARL3 protein solution (1mg/ml) containing 20mM Tris-HCl buffer (pH8.0), 30% glycerol, 0.1M NaCl, 1mM DTT and 0.1mM PMSF.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

MGSSHHHHHH SSGLVPRGSH MGSHMGLLSI LRKLKSAPDQ EVRILLLGLD NAGKTTLLKQ LASEDISHIT PTQGFNIKSV QSQGFKLNVW DIGGQRKIRP YWKNYFENTD ILIYVIDSAD RKRFEETGQE LAELLEEEKL SCVPVLIFAN KQDLLTAAPA SEIAEGLNLH TIRDRVWQIQ SCSALTGEGV QDGMNWVCKN VNAKKK.

Storage Instruction

Reconstituted store at -20°C or -80°C.We recommend that single use aliquots are prepared to avoid freeze-thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution

References

Not Available

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ARL3

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