ARL11

Alternative Names: ADP-ribosylation factor-like protein 11, ARL11, ADP-ribosylation factor-like tumor suppressor protein 1, ARLTS1.

ARL11, a member of the ARF family of small GTPases known to play a role in human carcinogenesis, is a conserved guanine nucleotide binding protein that enhances the activity of choleratoxin's ADP-ribosyltransferase. It is involved in eukaryotic vesicular trafficking pathways and plays a key role in activating phospholipase D (PC-PLD). ARL11 is believed to function as a tumor suppressor and may regulate apoptosis.

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  • Sku: PSB-pro-884-5µg
  • Vendor: ProSpec-Tany
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Title

Product Details

Product Description

Recombinant Human ADP-Ribosylation Factor-Like 11 (ARL11) is a protein belonging to the ADP-ribosylation factor-like (ARL) family. With a molecular weight of approximately X kDa, ARL11 plays a role in intracellular vesicular trafficking and protein transport. It functions as a small GTPase, regulating the recruitment and activation of effector proteins involved in membrane trafficking pathways. ARL11's involvement in these cellular processes makes it a subject of interest in various biological and pathological contexts. Understanding the molecular mechanisms and functions of ARL11 can provide valuable insights into cellular transport processes and potentially contribute to the development of therapeutic strategies.

Current Lead Time

7-14 Days

Product Specifications

Species
Human
Expression System E. coli
Purity 90% by SDS-PAGE
Activity
Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
23.6 kDa
Structure Monomer
Endotoxin Concentration
Not Available
Purification Method Not Available
Form
Frozen
Formulation ARL11 protein solution (0.5mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 5mM DTT,30% glycerol, 100mM NaCl and 1mM EDTA.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

MGSSHHHHHH SSGLVPRGSH MGSVNSRGHK AEAQVVMMGL DSAGKTTLLY KLKGHQLVET LPTVGFNVEP LKAPGHVSLT LWDVGGQAPL RASWKDYLEG TDILVYVLDS TDEARLPESA AELTEVLNDP NMAGVPFLVL ANKQEAPDAL PLLKIRNRLS LERFQDHCWE LRGCSALTGE GLPEALQSLW SLLKSRSCMC LQARAHGAER GDSKRS.

Storage Instruction

Reconstituted store at -20°C or -80°C.We recommend that single use aliquots are prepared to avoid freeze-thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution

References

Not Available

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ARL11

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