ARHGEF39

Alternative Names: ARHGEF39, C9orf100, Rho guanine nucleotide exchange factor 39, RP11-331F9.7

Recombinant Human Rho Guanine Nucleotide Exchange Factor 39 (RHOGEF39) is a protein that belongs to the Rho guanine nucleotide exchange factor (RhoGEF) family. RhoGEFs play a vital role in regulating the activation of Rho GTPases, which are crucial for various cellular processes including cytoskeletal organization, cell migration, and gene expression. With a molecular weight of approximately X kDa, RHOGEF39 acts as a mediator in the exchange of GDP for GTP on Rho GTPases, thereby modulating their signaling pathways. Its precise functions and mechanisms of action are still being investigated, making it an intriguing target for further research in understanding cellular dynamics and potential therapeutic interventions.

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  • Sku: PSB-pro-2101-5µg
  • Vendor: ProSpec-Tany
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Title

Product Details

Product Description

Recombinant Human Rho Guanine Nucleotide Exchange Factor 39 (RHOGEF39) is a protein that belongs to the Rho guanine nucleotide exchange factor (RhoGEF) family. RhoGEFs play a vital role in regulating the activation of Rho GTPases, which are crucial for various cellular processes including cytoskeletal organization, cell migration, and gene expression. With a molecular weight of approximately X kDa, RHOGEF39 acts as a mediator in the exchange of GDP for GTP on Rho GTPases, thereby modulating their signaling pathways. Its precise functions and mechanisms of action are still being investigated, making it an intriguing target for further research in understanding cellular dynamics and potential therapeutic interventions.

Current Lead Time

7-14 Days

Product Specifications

Species
Human
Expression System E. coli
Purity 85.0% by SDS-PAGE
Activity
Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
40.7 kDa
Structure Monomer
Endotoxin Concentration
Not Available
Purification Method Not Available
Form
Frozen
Formulation ARHGEF39 protein solution (1mg/ml) containing 20mM Tris-HCl buffer (pH 8.0) and 10% glycerol.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

MGSSHHHHHH SSGLVPRGSH MGSMELSCPG SRCPVQEQRA RWERKRACTA RELLETERRY QEQLGLVATY FLGILKAKGT LRPPERQALF GSWELIYGAS QELLPYLEGG CWGQGLEGFC RHLELYNQFA ANSERSQTTL QEQLKKNKGF RRFVRLQEGR PEFGGLQLQD LLPLPLQRLQ QYENLVVALA ENTGPNSPDH QQLTRAARLI SETAQRVHTI GQKQKNDQHL RRVQALLSGR QAKGLTSGRW FLRQGWLLVV PPHGEPRPRM FFLFTDVLLM AKPRPPLHLL RSGTFACKAL YPMAQCHLSR VFGHSGGPCG GLLSLSFPHE KLLLMSTDQE ELSRWYHSLT WAISSQKN.

Storage Instruction

Reconstituted store at -20°C or -80°C.We recommend that single use aliquots are prepared to avoid freeze-thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution

References

Not Available

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ARHGEF39

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