APOC1

Alternative Names: Apolipoprotein C-I, Apolipoprotein C1, Apo-CI, ApoC-I, APOC1.

APOC1 is a liver-expressed protein belonging to the apolipoprotein C family, mainly found in plasma. It plays a key role in facilitating the exchange of esterified cholesterol among lipoproteins and aiding in the removal of cholesterol from tissues. When monocytes differentiate into macrophages, APOC1 is activated. Its primary function is to inhibit CETP by modifying the electric charge of HDL molecules. Additionally, APOC1 binds to free fatty acids and decreases their intracellular esterification.

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  • Sku: PSB-cyt-812-2µg
  • Vendor: ProSpec-Tany
$60.00 USD
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Title

Product Details

Product Description

Recombinant Human Apolipoprotein C-I is a protein belonging to the apolipoprotein family, which plays a key role in lipid metabolism and transport. With a molecular weight of approximately 6.6 kDa, Apolipoprotein C-I is involved in regulating the levels of triglycerides and cholesterol in the bloodstream. This protein is essential for maintaining proper lipid homeostasis and is often used in research studies to better understand lipid-related disorders and diseases.

Current Lead Time

7-14 Days

Product Specifications

Species
Human
Expression System E. coli
Purity 90% by SDS-PAGE
Activity
Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
N/A
Structure Dimer
Endotoxin Concentration
Not Available
Purification Method Not Available
Form
Frozen
Formulation APOC1 protein solution (0.25mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 0.15M NaCl and 10% glycerol.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

MGSSHHHHHH SSGLVPRGSH MGSTPDVSSA LDKLKEFGNT LEDKARELIS RIKQSELSAK MREWFSETFQ KVKEKLKIDS.

Storage Instruction

Reconstituted store at -20°C or -80°C.We recommend that single use aliquots are prepared to avoid freeze-thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution

References

Not Available

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APOC1

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