APOBEC4

Alternative Names: Not Available

Recombinant Human Apolipoprotein B mRNA Editing Enzyme, Catalytic Polypeptide-Like 4 (APOBEC4) is a member of the APOBEC family of proteins. APOBEC4 is a catalytic polypeptide that plays a role in mRNA editing, specifically in the post-transcriptional modification of apolipoprotein B (APOB) mRNA. This protein is involved in the conversion of cytidine to uridine, leading to the creation of a premature stop codon in the APOB mRNA, thereby preventing the synthesis of a full-length APOB protein. APOBEC4 has a molecular weight of approximately 25 kilodaltons.

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  • Sku: PSB-pro-1787-5µg
  • Vendor: ProSpec-Tany
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Title

Product Details

Product Description

Recombinant Human Apolipoprotein B mRNA Editing Enzyme, Catalytic Polypeptide-Like 4 (APOBEC4) is a member of the APOBEC family of proteins. APOBEC4 is a catalytic polypeptide that plays a role in mRNA editing, specifically in the post-transcriptional modification of apolipoprotein B (APOB) mRNA. This protein is involved in the conversion of cytidine to uridine, leading to the creation of a premature stop codon in the APOB mRNA, thereby preventing the synthesis of a full-length APOB protein. APOBEC4 has a molecular weight of approximately 25 kilodaltons.

Current Lead Time

7-14 Days

Product Specifications

Species
Human
Expression System E. coli
Purity 85.0% by SDS-PAGE
Activity
Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
N/A
Structure Monomer
Endotoxin Concentration
Not Available
Purification Method Not Available
Form
Frozen
Formulation APOBEC4 protein solution (1mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 0.4M UREA and 10% glycerol.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

MGSSHHHHHH SSGLVPRGSH MGSMEPIYEE YLANHGTIVK PYYWLSFSLD CSNCPYHIRT GEEARVSLTE FCQIFGFPYG TTFPQTKHLT FYELKTSSGS LVQKGHASSC TGNYIHPESM LFEMNGYLDS AIYNNDSIRH IILYSNNSPC NEANHCCISK MYNFLITYPG ITLSIYFSQL YHTEMDFPAS AWNREALRSL ASLWPRVVLS PISGGIWHSV LHSFISGVSG SHVFQPILTG RALADRHNAY EINAITGVKP YFTDVLLQTK RNPNTKAQEA LESYPLNNAF PGQFFQMPSG QLQPNLPPDL RAPVVFVLVP LRDLPPMHMG QNPNKPRNIV RHLNMPQMSF QETKDLGRLP TGRSVEIVEI TEQFASSKEA DEKKKKKGKK

Storage Instruction

Reconstituted store at -20°C or -80°C.We recommend that single use aliquots are prepared to avoid freeze-thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution

References

Not Available

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APOBEC4

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