APOA5, HEK

Alternative Names: Apolipoprotein A-V, Apo-AV, ApoA-V, Apolipoprotein A5, APOA5, Regeneration-associated protein 3, RAP3, APOAV.

ApoA5 is a key regulator of serum triglyceride levels. Knock-out of ApoA5 in mice led to a significant increase in triglycerides, while a human ApoA5 knock-in model resulted in lower triglyceride levels. Peroxisome proliferators-activated receptoragonists, used to reduce triglycerides, increased ApoA5 mRNA expression. Limited knowledge exists about ApoA5 protein in human serum, but recent findings show it can be detected using specific antibodies, albeit at lower levels compared to other apolipoproteins.

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  • Sku: PSB-cyt-025-2µg
  • Vendor: ProSpec-Tany
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Safety Data Sheet
UniProt Listing
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Product Details

Product Description

Recombinant Human Apolipoprotein A-V, HEK is a protein belonging to the apolipoprotein family, specifically apolipoprotein A. It is produced using human embryonic kidney cells (HEK) through recombinant technology. This protein plays a significant role in lipid metabolism and is involved in the regulation of plasma triglyceride levels. Recombinant Human Apolipoprotein A-V, HEK has a molecular weight of approximately 37 kDa, making it a crucial component in the study of lipid-related disorders and metabolic diseases.

Current Lead Time

7-14 Days

Product Specifications

Species
 Human
Expression System HEK 293
Purity 70% by SDS-PAGE
Activity
 Not Available
Activity Assay
Animal Component Free (ACF) No
Molecular Weight
 N/A
Structure Homodimer
Endotoxin Concentration
 Not Available
Purification Method Not Available
Form
 Lyophilized
Formulation APOA5 Human was filtered (0.4µm) and lyophilized from 0.5 mg/ml supplied in 20mM TRIS and 50mM NaCl, pH 7.5

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

RKGFWDYFSQ TSGDKGRVEQ IHQQKMAREP ATLKDSLEQD LNNMNKFLEK LRPLSGSEAP RLPQDPVGMR RQLQEELEEV KARLQPYMAE AHELVGWNLE GLRQQLKPYT MDLMEQVALR VQELQEQLRV VGEDTKAQLL GGVDEAWALL QGLQSRVVHH TGRFKELFHP YAESLVSGIG RHVQELHRSV APHAPASPAR LSRCVQVLSR KLTLKAKALH ARIQQNLDQL REELSRAFAG TGTEEGAGPD PQMLSEEVRQ RLQAFRQDTY LQIAAFTRAI DQETEEVQQQ LAPPPPGHSA FAPEFQQTDS GKVLSKLQAR LDDLWEDITH SLHDQGHSHL GDPAAADYKD DDDK

Storage Instruction

Store lyophilized APOA5 Human at -20°C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles. Reconstituted APOA5 Human can be stored at 4°C for a limited period of time; it does not show any change after two weeks at 4°C. Store lyophilized APOA5 Human at -20°C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles. Reconstituted APOA5 Human can be stored at 4°C for a limited period of time; it does not show any change after two weeks at 4°C.

Sample Prep Instruction

It is recommended to add deionized water to prepare a working stock solution of approximately 0.5mg/ml and let the lyophilized pellet dissolve completely. Product is not sterile! Please filter the product by an appropriate sterile filter before using it on cell culture.

References

Not Available
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