• Home
  • Apo Transferrin

Apo Transferrin

Alternative Names: Transferrin, Serotransferrin, Siderophilin, Beta-1-metal-binding globulin, TF, PRO1557, PRO2086, DKFZp781D0156, Apo Transferrin, ATF.

Transferrin is a vital protein in vertebrate serum that transports iron to cells by binding to a specific membrane receptor called CD71. Most cells growing in tissue culture require transferrin, as it serves as a growth factor by interacting with transferrin receptors on proliferating cells. This interaction is necessary for cells to initiate and maintain DNA synthesis. In addition to its role in iron transport, transferrin also functions as a cytokine, performing tasks unrelated to carrying iron. Human Transferrin is crucial for the in vitro cultivation of mammalian cells, supporting long-term growth and acting as a detoxifying agent by binding to metal ions. It is commonly used as a nutrient in fermentation media for the production of recombinant proteins and biopharmaceuticals. Furthermore, Human Transferrin finds applications in molecular weight determination, affinity purification of anti-human transferrin antibodies, and receptor-mediated transfection of molecules like DNA into cells.

  •
  • Sku: PSB-pro-325-500mg
  • Vendor: ProSpec-Tany
$400.00 USD
Shipping calculated at checkout.

Contact us directly for international purchases.

Title
Report Product Listing Issue (e.g. Missing Data, or Questions)
Safety Data Sheet
UniProt Listing
NCBI Link

Product Details

Product Description

Human Apo Transferrin is a glycoprotein that plays a vital role in iron metabolism. Belonging to the transferrin family, it functions as a carrier protein for iron ions in the bloodstream. With a molecular weight of approximately 77 kDa, it is synthesized in the liver and secreted into the blood, where it binds to ferric iron and transports it to cells expressing transferrin receptors. This interaction is crucial for maintaining iron homeostasis in the body, ensuring proper oxygen transport and cellular functions.

Current Lead Time

7-14 Days

Product Specifications

Species
 Human
Expression System Human Serum
Purity 98% by SDS-PAGE
Activity
 Not Available
Activity Assay
Animal Component Free (ACF) No
Molecular Weight
 N/A
Structure Homodimer
Endotoxin Concentration
 Not Available
Purification Method Not Available
Form
 Lyophilized
Formulation
The protein was lyophilized from 20mM NH4HC03 solution. May contain traces of buffer salts.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

Check Uniprot Link

Storage Instruction

Store the lyophilized Apo Transferrin between 2-8°C, do not freeze. Upon reconstitution Apo Transferrin should be stored at 4°C between 2-7 days and for future use below -18°C.Please prevent freeze-thaw cycles.

Sample Prep Instruction

It is recommended to reconstitute the lyophilized Apo Transferrin in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

References

Not Available
View full details

Apo Transferrin
SUBHEADING

Recently viewed products