ANXA8L1

Alternative Names: Annexin A8-like protein 2, ANXA8, annexin A8L2, bA145E20.2

ANXA8L2 is a calcium-dependent phospholipid binding protein belonging to the annexin family. Members of this family regulate ion flux, endocytosis and exocytosis, and cellular adhesion. ANXA8L2 is a membrane binding protein with properties such as voltage-sensitive calcium channel activity, ion selectivity, and membrane fusion. Overexpression of ANXA8L2 is associated with acute myelocytic leukemia. Additionally, ANXA8L2 may act as an anticoagulant by indirectly inhibiting the thromboplastin-specific complex.

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  • Sku: PSB-pro-1138-1µg
  • Vendor: ProSpec-Tany
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Title

Product Details

Product Description

Recombinant Human Annexin A8 Like-1 (ANXA8L1) is a protein that belongs to the annexin family, a group of calcium-dependent phospholipid-binding proteins. With a molecular weight of approximately X kDa, ANXA8L1 plays a role in various cellular processes, including membrane organization, vesicle trafficking, and signal transduction. This protein is involved in the regulation of cell growth, differentiation, and apoptosis. Understanding the functions and mechanisms of ANXA8L1 can provide valuable insights into its potential implications in disease pathogenesis and therapeutic interventions.

Current Lead Time

7-14 Days

Product Specifications

Species
Human
Expression System E. coli
Purity 90% by SDS-PAGE
Activity
Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
N/A
Structure Monomer
Endotoxin Concentration
Not Available
Purification Method Not Available
Form
Frozen
Formulation The ANXA8L1 solution (1mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 0.1M NaCl, 1mM DTT and 10% glycerol.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

MGSSHHHHHH SSGLVPRGSH MGSHMAWWKA WIEQEGVTVK SSSHFNPDPD AETLYKAMKG IGTNEQAIID VLTKRSNTQR QQIAKSFKAQ FGKDLTETLK SELSGKFERL IVALMYPPYR YEAKELHDAM KGLGTKEGVI IEILASRTKN QLREIMKAYE EDYGSSLEED IQADTSGYLE RILVCLLQGS RDDVSSFVDP ALALQDAQDL YAAGENIRGT DEMKFITILC TRSATHLLRV FEEYEKIANK SIEDSIKSET HGSLEEAMLT VVKCTQNLHS YFAERLYYAM KGAGTRDGTL IRNIVSRSEI DLNLIKCHFK KMYGKTLSSM IMEDTSGDYK NALLSLVGSD P

Storage Instruction

Reconstituted store at -20°C or -80°C.We recommend that single use aliquots are prepared to avoid freeze-thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution

References

Not Available

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ANXA8L1

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