ANXA4

Alternative Names: ANX4, ANXA4, Annexin-IV, Lipocortin-4, Lipocortin-IV, Annexin-4, Annexin A4, Endonexin I, Chromobindin-4, Protein II, P32.5, Placental anticoagulant protein II, PAP-II, PP4-X, 35-beta calcimedin, Carbohydrate-binding protein p33/p41, PIG28, ZAP36, MGC75105, DKFZp686H02120.

ANXA4 is a calcium-dependent phospholipid binding protein belonging to the annexin family. It shares similarities in structure and genetic organization with other proteins in its family, with identity ranging from 45% to 59%. ANXA4 has shown interaction with ATP and exhibits both in vitro anticoagulant and phospholipase A2 inhibitory activities. Its expression is limited to epithelial cells. Moreover, ANXA4 acts as a calcium/phospholipid-binding protein that facilitates membrane fusion and plays a role in exocytosis.

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  • Sku: PSB-pro-766-2µg
  • Vendor: ProSpec-Tany
$60.00 USD
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Safety Data Sheet
UniProt Listing
NCBI Link

Product Details

Product Description

Recombinant Human Annexin A4 is a protein that belongs to the annexin family, which consists of calcium-dependent phospholipid-binding proteins. With a weight of approximately 36 kDa, this protein plays a significant role in various cellular processes, including membrane organization, vesicle trafficking, and signal transduction. Its calcium-dependent binding ability enables it to interact with phospholipids, thereby modulating membrane dynamics and participating in intracellular signaling pathways. Recombinant Human Annexin A4 is a valuable tool for studying the functional properties and regulatory mechanisms of this protein in various biological contexts.

Current Lead Time

7-14 Days

Product Specifications

Species
 Human
Expression System E. coli
Purity 90% by SDS-PAGE
Activity
 Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
 N/A
Structure Homodimer
Endotoxin Concentration
 Not Available
Purification Method Not Available
Form
 Frozen
Formulation The ANXA4 protein solution contains 20mM Tris-HCl, pH-8 and 20% glycerol, 0.2M NaCl.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

MAMATKGGTV KAASGFNAME DAQTLRKAMK GLGTDEDAII SVLAYRNTAQ RQEIRTAYKS TIGRDLIDDL KSELSGNFEQ VIVGMMTPTV LYDVQELRRA MKGAGTDEGC LIEILASRTP EEIRRISQTY QQQYGRSLED DIRSDTSFMF QRVLVSLSAG GRDEGNYLDD ALVRQDAQDL YEAGEKKWGT DEVKFLTVLC SRNRNHLLHV FDEYKRISQK DIEQSIKSET SGSFEDALLA IVKCMRNKSA YFAEKLYKSM KGLGTDDNTL IRVMVSRAEI DMLDIRAHFK RLYGKSLYSF IKGDTSGDYR KVLLVLCGGD D.

Storage Instruction

Reconstituted store at -20°C or -80°C.We recommend that single use aliquots are prepared to avoid freeze-thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution
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References

Not Available
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ANXA4
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