ANXA13

Alternative Names: Actin Filament Associated Protein 1, 110 kDa actin filament-associated protein, AFAP-110, AFAP1, AFAP, Actin filament-associated protein 1.

AFAP1, a protein that binds to Src, is involved in modulating actin filament integrity in response to cellular signals. It acts as an adapter by connecting Src family members to actin filaments. AFAP1's involvement in prostate adenocarcinoma includes regulating cell-matrix adhesions and migration.

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  • Sku: PSB-pro-197-5µg
  • Vendor: ProSpec-Tany
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Title

Product Details

Product Description

Recombinant Human Annexin A13 is a protein that belongs to the annexin family, a group of calcium-dependent phospholipid-binding proteins. With a molecular weight of approximately 36 kDa, Annexin A13 plays a role in various cellular processes, including membrane organization, vesicle trafficking, and signal transduction. This recombinant protein is produced through genetic engineering techniques, making it a valuable tool for research purposes. Its structural and functional characteristics make it an intriguing target for investigating the intricate mechanisms underlying cellular dynamics.

Current Lead Time

7-14 Days

Product Specifications

Species
Human
Expression System E. coli
Purity 80% by SDS-PAGE
Activity
Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
N/A
Structure Homodimer
Endotoxin Concentration
Not Available
Purification Method Not Available
Form
Frozen
Formulation The AFAP1 solution (0.5mg/1ml) contains 20mM Tris-HCl buffer (pH 8.0), 10% glycerol and 0.4M Urea.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

MGSSHHHHHH SSGLVPRGSH MGCSGPVDSE CPPPPSSPVH KAELEKKLSS ERPSSDGEGV VENGITTCNG KEQVKRKKSS KSEAKGTVSK VTGKKITKII SLGKKKPSTD EQTSSAEEDV PTCGYLNVLS NSRWRERWCR VKDNKLIFHK DRTDLKTHIV SIPLRGCEVI PGLDCKHPLT FRLLRNGQEV AVLEASSSED MGRWIGILLA ETGSSTDPEA LHYDYIDVEM SASVIQTAKQ TFCFMNRRVI SANPYLGGTS NGYAHPSGTA LHYDDVPCIN GSLRGKKPPV ASNGVTGKGK TLSSQPKKAD PAAVVKRTGS NAAQYKYGKN RVEADAKRLQ TKEEELLKRK EALRNRLAQL.

Storage Instruction

Reconstituted store at -20°C or -80°C.We recommend that single use aliquots are prepared to avoid freeze-thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution

References

Not Available

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ANXA13

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