ANTXR2

Alternative Names: Anthrax toxin receptor 2, ANTXR2, Capillary morphogenesis gene 2 protein, CMG-2, CMG2, m CMG2, HFS, ISH, JHF.

The role of ANTXR2, or anthrax toxin receptor 2, includes aiding in the development of capillaries, facilitating the attachment of anthrax toxin to cells, and initiating illness. It is also vital for the interaction between cells and laminin as well as the extracellular matrix.

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  • Sku: PSB-pro-2022-2µg
  • Vendor: ProSpec-Tany
$60.00 USD
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Title

Product Details

Product Description

Recombinant Human Anthrax Toxin Receptor 2 is a protein that plays a significant role in the pathogenesis of anthrax infection. Belonging to the immunoglobulin superfamily, this receptor facilitates the entry of anthrax toxins into host cells, thereby enabling the progression of the disease. With a molecular weight of approximately X kDa, this protein acts as a receptor for protective antigen (PA), a key component of the anthrax toxin complex. By binding to PA, Recombinant Human Anthrax Toxin Receptor 2 contributes to the internalization of the toxin, ultimately leading to the detrimental effects associated with anthrax infection.

Current Lead Time

7-14 Days

Product Specifications

Species
Human
Expression System E. coli
Purity 85 % by SDS-PAGE
Activity
Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
N/A
Structure Homodimer
Endotoxin Concentration
Not Available
Purification Method Not Available
Form
Frozen
Formulation The ANTXR2 solution (0.25mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 10% glycerol, 1mM DTT and 0.1M NaCl.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

MGSSHHHHHH SSGLVPRGSH MGSQEQPSCR RAFDLYFVLD KSGSVANNWI EIYNFVQQLA ERFVSPEMRL SFIVFSSQAT IILPLTGDRG KISKGLEDLK RVSPVGETYI HEGLKLANEQ IQKAGGLKTS SIIIALTDGK LDGLVPSYAE KEAKISRSLG ASVYCVGVLD FEQAQLERIA DSKEQVFPVK GGFQALKGII NSILAQSCTE ILELQPSSVC VGEEFQIVLS GRGFMLGSRN GSVLCTYTVN ETYTTSVKPV SVQLNSMLCP APILNKAGET LDVSVSFNGG KSVISGSLIV TATECSN.

Storage Instruction

Reconstituted store at -20°C or -80°C.We recommend that single use aliquots are prepared to avoid freeze-thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution

References

Not Available

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ANTXR2

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