ANGPTL4

Alternative Names: Fasting- Induced Adipose Factor, FIAF, Hepatic Fibrinogen/Angiopoietin-Related Protein, HFARP, PPARG Angiopoietin-Related Protein, PGAR, ANGPTL2, ARP4, ANGPTL4, NL2, pp1158

FIAF, also known as ANGPTL4, PGAR, or HFARP, is a protein that is up-regulated by fasting, peroxisome proliferator-activated receptor agonists, and hypoxia. It is found in both human and mouse blood plasma in native and truncated forms. The native form is detected in human adipose tissue and SGBS adipocytes, while the truncated form is associated with differentiation of mouse 3T3-L1 adipocytes and produced in human liver. FIAF levels in human blood plasma are mainly in the truncated form (FIAF-S2), and treatment can increase these levels. Levels of both forms of FIAF vary between individuals but are not influenced by prolonged semistarvation or associated with body mass index.

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  • Sku: PSB-cyt-249-2µg
  • Vendor: ProSpec-Tany
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Safety Data Sheet
UniProt Listing
NCBI Link

Product Details

Product Description

Recombinant Human Angiopoietin-like Protein 4 (ANGPTL4) is a member of the angiopoietin-like protein family, which plays a role in regulating lipid metabolism and energy homeostasis. With a molecular weight of approximately 50 kDa, ANGPTL4 is involved in the inhibition of lipoprotein lipase activity, leading to the regulation of plasma triglyceride levels. This protein has been studied for its potential implications in metabolic disorders and cardiovascular diseases.

Current Lead Time

7-14 Days

Product Specifications

Species
 Human
Expression System E. coli
Purity 95% by SDS-PAGE
Activity
 Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
 N/A
Structure Dimer
Endotoxin Concentration
 Not Available
Purification Method Not Available
Form
 Lyophilized
Formulation Filtered and lyophilized from 0.5 mg/ml in 0.05M Acetate buffer pH-4.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

MRGSHHHHHH GMASHMGPVQ SKSPRFASWD EMNVLAHGLL QLGQGLREHA ERTRSQLSAL ERRLSACGSA CQGTEGSTDL PLAPESRVDP EVLHSLQTQL KAQNSRIQQL FHKVAQQQRH LEKQHLRIQH LQSQFGLLDH KHLDHEVAKP ARRKRLPEMA QPVDPAHNVS RLHRLPRDCQ ELFQVGERQS GLFEIQPQGS PPFLVNCKMT SDGGWTVIQR.

Storage Instruction

Store lyophilized Angiopoietin-like Protein 4 Human recombinant at -20°C. Aliquot the ANGPTL4 after reconstitution to avoid repeated freezing/thawing cycles. Reconstituted ANGPTL4 can be stored at 4°C for a limited period of time; it does not show any change after two weeks at 4°C. Store lyophilized Angiopoietin-like Protein 4 Human recombinant at -20°C. Aliquot the ANGPTL4 after reconstitution to avoid repeated freezing/thawing cycles. Reconstituted ANGPTL4 can be stored at 4°C for a limited period of time; it does not show any change after two weeks at 4°C.

Sample Prep Instruction

Add 0.1M Acetate buffer pH4 and let the lyophilized pellet dissolve completely. For conversion into higher pH value, we recommend intensive dilution by relevant buffer to a concentration of 10μg/ml. In higher concentrations the solubility of this antigen is limited.

References

Not Available
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ANGPTL4
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