ANGPTL3 (243-460)

Alternative Names: Not Available

ANGPTL3 and ANGPTL4, secreted mainly by the liver, regulate triglyceride metabolism by inhibiting the lipolysis of triglyceride-rich lipoproteins. Experimental data shows that these proteins play a role in regulating circulating triglyceride levels during feeding and fasting states by inhibiting Lipoprotein lipase (LPL). The molecular structure of ANGPTL3 is similar to angiopoietins, and deletion mutants of human Angiopoietin 5 have shown that the N-terminal domain, not the C-terminal fibrinogen-like domain, increases plasma triglyceride levels in mice.

Skip to product information
  • Sku: PSB-cyt-902-5µg
  • Vendor: ProSpec-Tany
$60.00 USD
 per 
Shipping calculated at checkout.

Contact us directly for international purchases.

Title

Product Details

Product Description

Recombinant Human Angiopoietin-like Protein 3, (243-460 a.a.) is a member of the angiopoietin-like protein family. It is a protein fragment consisting of amino acids 243 to 460. This protein plays a role in lipid metabolism and has been studied for its potential implications in cardiovascular diseases. With a molecular weight of approximately 25 kDa, Recombinant Human Angiopoietin-like Protein 3 (243-460 a.a.) is commonly used in research settings to investigate its biological functions and potential therapeutic applications.

Current Lead Time

7-14 Days

Product Specifications

Species
Human
Expression System E. coli
Purity 90% by SDS-PAGE
Activity
Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
27.7 kDa
Structure Homodimer
Endotoxin Concentration
Not Available
Purification Method Not Available
Form
Frozen
Formulation ANGPTL3 protein solution (1mg/ml) containing 20mM Tris-HCl (pH8.0) and 10% glycerol.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

MGSSHHHHHH SSGLVPRGSH MPAECTTIYN RGEHTSGMYA IRPSNSQVFH VYCDVISGSP WTLIQHRIDG SQNFNETWEN YKYGFGRLDG EFWLGLEKIY SIVKQSNYVL RIELEDWKDN KHYIEYSFYL GNHETNYTLH LVAITGNVPN AIPENKDLVF STWDHKAKGH FNCPEGYSGG WWWHDECGEN NLNGKYNKPR AKSKPERRRG LSWKSQNGRL YSIKSTKMLI HPTDSESFE.

Storage Instruction

Reconstituted store at -20°C or -80°C.We recommend that single use aliquots are prepared to avoid freeze-thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution

References

Not Available

View full details

ANGPTL3 (243-460)

SUBHEADING

Recently viewed products