AKR7A2

Alternative Names: Aflatoxin B1 aldehyde reductase member 2, AFB1-AR1, AFAR, AFAR1, AFB1 aldehyde reductase 1, AKR7, Aldoketoreductase 7, AKR7A2, Succinic semialdehyde reductase, SSA reductase.

Recombinant Human Aldo-Keto Reductase Family 7 Member A2 (AKR7A2) is a protein belonging to the aldo-keto reductase family. With a molecular weight of approximately 38 kDa, AKR7A2 plays a role in the detoxification of aldehydes and ketones in various cellular processes. This enzyme is involved in the reduction of carbonyl compounds and is essential for maintaining cellular homeostasis.

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  • Sku: PSB-enz-485-5µg
  • Vendor: ProSpec-Tany
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Title

Product Details

Product Description

Recombinant Human Aldo-Keto Reductase Family 7 Member A2 (AKR7A2) is a protein belonging to the aldo-keto reductase family. With a molecular weight of approximately 38 kDa, AKR7A2 plays a role in the detoxification of aldehydes and ketones in various cellular processes. This enzyme is involved in the reduction of carbonyl compounds and is essential for maintaining cellular homeostasis.

Current Lead Time

7-14 Days

Product Specifications

Species
Human
Expression System E. coli
Purity 90% by SDS-PAGE
Activity
Specific activity: approximately 0.25-0.3 units/mg. Enzymatic activity was confirmed by measuring the amount of enzyme catalyzing the oxidation of 1 micromole NADPH per minute at 25C. Specific activity was expressed as units/mg protein.
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
N/A
Structure Homodimer
Endotoxin Concentration
Not Available
Purification Method Not Available
Form
Frozen
Formulation The AKR7A2 solution contains 20mM Tris-HCl pH-8, 1mM DTT and 20% glycerol.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSELEM LSAASRVVSR AAVHCALRSP PPEARALAMS RPPPPRVASV LGTMEMGRRM DAPASAAAVR AFLERGHTEL DTAFMYSDGQ SETILGGLGL GLGGGDCRVK IATKANPWDG KSLKPDSVRS QLETSLKRLQ CPQVDLFYLH APDHGTPVEE TLHACQRLHQ EGKFVELGLS NYASWEVAEI CTLCKSNGWI LPTVYQGMYN ATTRQVETEL FPCLRHFGLR FYAYNPLAGG LLTGKYKYED KDGKQPVGRF FGNSWAETYR NRFWKEHHFE AIALVEKALQ AAYGASAPSV TSAALRWMYH HSQLQGAHGD AVILGMSSLE QLEQNLAATE EGPLEPAVVD AFNQAWHLVA HECPNYFR.

Storage Instruction

Reconstituted store at -20°C or -80°C.We recommend that single use aliquots are prepared to avoid freeze-thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution

References

Not Available

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AKR7A2

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