AITR

Alternative Names: Tumor necrosis factor receptor superfamily member 18, AITR, CD357, GITR, GITR-D, Activation-inducible TNFR family receptor, Glucocorticoid-induced TNFR-related protein, UNQ319/PRO364.

Recombinant Human AITR is a member of the TNF receptor superfamily, specifically the tumor necrosis factor receptor superfamily member 9 (TNFRSF9). It is a protein weighing approximately 48 kDa and is involved in the regulation of immune responses. Recombinant Human AITR plays a role in the activation of T cells and the induction of immune tolerance. Its interaction with its ligand, CD137L, leads to the activation of multiple signaling pathways that modulate immune function.

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  • Sku: PSB-cyt-925-2µg
  • Vendor: ProSpec-Tany
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Title

Product Details

Product Description

Recombinant Human AITR is a member of the TNF receptor superfamily, specifically the tumor necrosis factor receptor superfamily member 9 (TNFRSF9). It is a protein weighing approximately 48 kDa and is involved in the regulation of immune responses. Recombinant Human AITR plays a role in the activation of T cells and the induction of immune tolerance. Its interaction with its ligand, CD137L, leads to the activation of multiple signaling pathways that modulate immune function.

Current Lead Time

7-14 Days

Product Specifications

Species
Human
Expression System Sf9 - Baculovirus cells
Purity 95% by SDS-PAGE
Activity
Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
15.6 kDa
Structure Dimer
Endotoxin Concentration
Not Available
Purification Method Not Available
Form
Frozen
Formulation AITR protein solution (0.5mg/ml) containing Phosphate Buffered Saline (pH 7.4) and 10% glycerol.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

QRPTGGPGCG PGRLLLGTGT DARCCRVHTT RCCRDYPGEE CCSEWDCMCV QPEFHCGDPC CTTCRHHPCP PGQGVQSQGK FSFGFQCIDC ASGTFSGGHE GHCKPWTDCT QFGFLTVFPG NKTHNAVCVP GSPPAEPLEH HHHHH.

Storage Instruction

Reconstituted store at -20°C or -80°C.We recommend that single use aliquots are prepared to avoid freeze-thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution

References

Not Available

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AITR

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