AIDA

Alternative Names: C1orf80, RP11-378J18.7, Axin interactor, Axin interaction partner and dorsalization antagonist, dorsalization-associated protein, AIDA.

AIDA is a protein that plays a role in ventralizing the embryo during development. It does this by inhibiting the activation of JNK (a protein that regulates cell death) by axin, another protein involved in cell signaling. AIDA achieves this by binding to axin and preventing it from forming dimers with other axin molecules. This action opposes a dorsalization pathway that is activated by the AXIN/JNK signaling pathway independently of the Wnt/beta-catenin pathway.

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  • Sku: PSB-pro-1370-2µg
  • Vendor: ProSpec-Tany
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Title

Product Details

Product Description

Recombinant Human Axin Interactor Dorsalization Associated (RHAXINIDA) is a protein that belongs to the Axin Interactor family. With a molecular weight of approximately X kDa, RHAXINIDA plays a significant role in the process of dorsalization during embryonic development. This protein is involved in the regulation of Wnt signaling pathway, which is crucial for cell fate determination and tissue patterning. RHAXINIDA's molecular weight and family association make it a subject of interest in various scientific studies aiming to understand the intricate mechanisms underlying embryogenesis and tissue differentiation.

Current Lead Time

7-14 Days

Product Specifications

Species
Human
Expression System E. coli
Purity 90% by SDS-PAGE
Activity
Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
37.4 kDa
Structure Homodimer
Endotoxin Concentration
Not Available
Purification Method Not Available
Form
Frozen
Formulation AIDA protein solution (0.25mg/ml) containing 20mM Tris-HCl buffer (pH8.0), 10% glycerol, 0.2M NaCl and 1mM DTT.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

MGSSHHHHHH SSGLVPRGSH MGSMSEVTRS LLQRWGASFR RGADFDSWGQ LVEAIDEYQI LARHLQKEAQ AQHNNSEFTE EQKKTIGKIA TCLELRSAAL QSTQSQEEFK LEDLKKLEPI LKNILTYNKE FPFDVQPVPL RRILAPGEEE NLEFEEDEEE GGAGAGSPDS FPARVPGTLL PRLPSEPGMT LLTIRIEKIG LKDAGQCIDP YITVSVKDLN GIDLTPVQDT PVASRKEDTY VHFNVDIELQ KHVEKLTKGA AIFFEFKHYK PKKRFTSTKC FAFMEMDEIK PGPIVIELYK KPTDFKRKKL QLLTKKPLYL HLHQTLHKE.

Storage Instruction

Reconstituted store at -20°C or -80°C.We recommend that single use aliquots are prepared to avoid freeze-thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution

References

Not Available

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AIDA

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