AHSG

Alternative Names: Alpha-2-HS-glycoprotein, Alpha-2-Z-globulin, Ba-alpha-2-glycoprotein, Fetuin-A, PRO2743, A2HS, AHS, FETUA, HSGA

AHSG, or fetuin-A, is a glycoprotein found in the blood that is made by liver cells. It belongs to a group of plasma binding proteins called fetuins. AHSG has various functions, including involvement in endocytosis, brain development, and the formation of bone tissue. It is primarily found in the immature cerebral cortex and bone marrow, suggesting a role in tissue development. However, its exact significance is still not completely understood. AHSG promotes endocytosis, possesses opsonic properties, and affects the mineral composition of bones. It has been shown to have an affinity for calcium and barium ions.

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  • Sku: PSB-pro-1450-2µg
  • Vendor: ProSpec-Tany
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Title

Product Details

Product Description

Recombinant Human Alpha-2-HS-Glycoprotein, also known as AHSG, is a protein that belongs to the albuminoid family. With a molecular weight of approximately 38-45 kDa, it is primarily synthesized in the liver and secreted into the bloodstream. AHSG plays a significant role in various physiological processes, including regulation of bone mineralization, inhibition of insulin receptor autophosphorylation, and modulation of immune responses. This recombinant protein has gained attention in biomedical research and therapeutic applications due to its potential involvement in several pathological conditions.

Current Lead Time

7-14 Days

Product Specifications

Species
Human
Expression System E. coli
Purity 90% by SDS-PAGE
Activity
Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
39.7 kDa
Structure Monomer
Endotoxin Concentration
Not Available
Purification Method Not Available
Form
Frozen
Formulation AHSG protein solution (0.5mg/ml) containing 20mM Tris-HCl buffer (pH8.0), 10% glycerol 0.1M NaCl and 1mM DTT.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

MGSSHHHHHH SSGLVPRGSH MGSAPHGPGL IYRQPNCDDP ETEEAALVAI DYINQNLPWG YKHTLNQIDE VKVWPQQPSG ELFEIEIDTL ETTCHVLDPT PVARCSVRQL KEHAVEGDCD FQLLKLDGKF SVVYAKCDSS PDSAEDVRKV CQDCPLLAPL NDTRVVHAAK AALAAFNAQN NGSNFQLEEI SRAQLVPLPP STYVEFTVSG TDCVAKEATE AAKCNLLAEK QYGFCKATLS EKLGGAEVAV TCTVFQTQPV TSQPQPEGAN EAVPTPVVDP DAPPSPPLGA PGLPPAGSPP DSHVLLAAPP GHQLHRAHYD LRHTFMGVVS LGSPSGEVSH PRKTRTVVQP SVGAAAGPVV PPCPGRIRHF KV.

Storage Instruction

Reconstituted store at -20°C or -80°C.We recommend that single use aliquots are prepared to avoid freeze-thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution

References

Not Available

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AHSG

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