AHCY

Alternative Names: EC 3.3.1.1, AdoHcyase, S-adenosyl-L-homocysteine hydrolase, SAHH, Adenosylhomocysteinase.

The enzyme AHCY plays a key role in the breakdown of S-adenosylhomocysteine (AdoHcy) into adenosine (Ado) and L-homocysteine (Hcy). This process is essential for maintaining the proper level of intracellular S-adenosylhomocysteine (SAH) needed for transmethylation reactions. Deficiency in AHCY can lead to hypermethioninemia.

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  • Sku: PSB-enz-532-5µg
  • Vendor: ProSpec-Tany
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Title

Product Details

Product Description

Recombinant Human Adenosylhomocysteinase is an enzyme that belongs to the adenosylhomocysteinase family. It plays a role in the regulation of S-adenosylhomocysteine, a byproduct of methylation reactions. With a molecular weight of approximately 45 kDa, Recombinant Human Adenosylhomocysteinase is involved in the breakdown of S-adenosylhomocysteine into adenosine and homocysteine. This enzyme is commonly used in research and biotechnological applications for its catalytic properties.

Current Lead Time

7-14 Days

Product Specifications

Species
Human
Expression System E. coli
Purity 95% by SDS-PAGE
Activity
Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
N/A
Structure Homodimer
Endotoxin Concentration
Not Available
Purification Method Not Available
Form
Frozen
Formulation AHCY Human solution containing 20mM Tris pH-8, & 10% glycerol.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

MGSSHHHHHH SSGLVPRGSH MSDKLPYKVA DIGLAAWGRK ALDIAENEMP GLMRMRERYS ASKPLKGARI AGCLHMTVET AVLIETLVTL GAEVQWSSCN IFSTQDHAAA AIAKAGIPVY AWKGETDEEY LWCIEQTLYF KDGPLNMILD DGGDLTNLIH TKYPQLLPGI RGISEETTTG VHNLYKMMAN GILKVPAINV NDSVTKSKFD NLYGCRESLI DGIKRATDVM IAGKVAVVAG YGDVGKGCAQ ALRGFGARVI ITEIDPINAL QAAMEGYEVT TMDEACQEGN IFVTTTGCID IILGRHFEQM KDDAIVCNIG HFDVEIDVKW LNENAVEKVN IKPQVDRYRL KNGRRIILLA EGRLVNLGCA MGHPSFVMSN SFTNQVMAQI ELWTHPDKYP VGVHFLPKKL DEAVAEAHLG KLNVKLTKLT EKQAQYLGMS CDGPFKPDHY RY.

Storage Instruction

Reconstituted store at -20°C or -80°C.We recommend that single use aliquots are prepared to avoid freeze-thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution

References

Not Available

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AHCY

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