Activin A, Plant-Active

Alternative Names: Inhba, Inhibin beta A, FSH releasing protein.

Activins, part of the TGF? family, are composed of homodimers or heterodimers of different ? subunit isoforms. Activin A, a mature form, consists of two betaA subunits, each with 116 amino acid residues. This protein is involved in various biological activities such as mesoderm induction, neural cell differentiation, bone remodelling, haematopoiesis, and reproductive physiology. Additionally, Activins play a role in the production and regulation of hormones like FSH, LH, GnRH, and ACTH. A variety of cell types have been identified as expressing Activin A, including fibroblasts, endothelial cells, hepatocytes, vascular smooth muscle cells, and others.

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  • Sku: PSB-cyt-414-1µg
  • Vendor: ProSpec-Tany
$60.00 USD
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Title

Product Details

Product Description

Current Lead Time

7-14 Days

Product Specifications

Species
Human
Expression System Nicotiana benthamiana
Purity 98% by SDS-PAGE
Activity
The biological activity of INHBA is measured by its ability to inhibit mouse plasmacytoma cell line (MPC-11) cells proliferation ([3H]thymidine incorporation). ED50<5ng/ml.
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
Structure Contact for Details
Endotoxin Concentration
Not Available
Purification Method Not Available
Form
Lyophilized freeze dried powder.
Formulation Active form Activin-A was lyophilized from a concentrated 1mg/ml protein solution containing 50mM Tris-HCl pH-7.4 Active form Activin-A was lyophilized from a concentrated 1mg/ml protein solution containing 50mM Tris-HCl pH-7.4

*For Research Use Only

Notes

Activins are homodimers or heterodimers of the different β subunit isoforms, part of the TGFβ family. Mature Activin A has two 116 amino acids residues βA subunits (βA-βA). Activin displays an extensive variety of biological activities, including mesoderm induction, neural cell differentiation, bone remodelling, haematopoiesis, and reproductive physiology. Activins takes part in the production and regulation of hormones such as FSH, LH, GnRH and ACTH. Cells that are identified to express Activin A include fibroblasts, endothelial cells, hepatocytes, vascular smooth muscle cells, macrophages, keratinocytes, osteoclasts, bone marrow monocytes, prostatic epithelium, neurons, chondrocytes, osteoblasts, Leydig cells, Sertoli cells, and ovarian granulosa cells.

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

HHHHHHGLECDGKVNICCKKQFFVSFKDIGWNDWIIAPSGYHANYCEGECPSHIAGTSGSSLSFHSTVINHYRMRGHSPFANLKSCCVPTKLRPMSMLYYDDGQNIIKKDIQNMIVEECGCS.

Storage Instruction

For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Repeated freezing and thawing is not recommended. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Repeated freezing and thawing is not recommended.

Sample Prep Instruction

INHBA protein should be reconstituted in distilled water to a concentration of 50 ug /ml. Due to the protein nature, dimmers and multimers may be observed.

References

Not Available

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Activin A, Plant-Active

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