Activin A, Active

Alternative Names: Inhba, Inhibin beta A, FSH releasing protein.

Discover the transformative power of Activin A, a vital member of the TGFβ family, composed of homodimers or heterodimers of distinct β subunit isoforms. Activin A boasts a robust structure with two 116-amino acid residues, βA-βA, driving its myriad biological functions. From inducing mesoderm to guiding neural cell differentiation, orchestrating bone remodeling, facilitating hematopoiesis, and influencing reproductive physiology, Activin A is indispensable. This versatile molecule also plays a pivotal role in hormone production and regulation, impacting FSH, LH, GnRH, and ACTH. Found in a diverse array of cells including fibroblasts, endothelial cells, hepatocytes, and more, Activin A exerts its influence across multiple physiological systems. Unleash the potential of Activin A today for enhanced cellular function and overall well-being.

Skip to product information
  • Sku: PSB-cyt-145-2µg
  • Vendor: ProSpec-Tany
$60.00 USD
 per 
Shipping calculated at checkout.

Contact us directly for international purchases.

Title

Product Details

Product Description

Current Lead Time

7-14 Days

Product Specifications

Species
Human
Expression System E. coli
Purity 95% by SDS-PAGE
Activity
Biological activity is assessed by the ability to induce cytotoxicity of MPC-11 cells and was found to be 8.8ng/ml corresponding to a specific activity of 1.1 x 105 units/mg.
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
Structure Contact for Details
Endotoxin Concentration
Not Available
Purification Method Not Available
Form
Lyophilized freeze dried powder.
Formulation Human Activin-A was lyophilized from a concentrated 1mg/ml protein solution containing 0.1% TFA.

*For Research Use Only

Notes

Activins are homodimers or heterodimers of the different β subunit isoforms, part of the TGFβ family. Mature Activin A has two 116 amino acids residues βA subunits (βA-βA). Activin displays an extensive variety of biological activities, including mesoderm induction, neural cell differentiation, bone remodelling, haematopoiesis, and reproductive physiology. Activins takes part in the production and regulation of hormones such as FSH, LH, GnRH and ACTH. Cells that are identified to express Activin A include fibroblasts, endothelial cells, hepatocytes, vascular smooth muscle cells, macrophages, keratinocytes, osteoclasts, bone marrow monocytes, prostatic epithelium, neurons, chondrocytes, osteoblasts, Leydig cells, Sertoli cells, and ovarian granulosa cells.

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

MGLECDGKVN ICCKKQFFVS FKDIGWNDWI IAPSGYHANY CEGECPSHIA GTSGSSLSFH STVINHYRMR GHSPFANLKS CCVPTKLRPM SMLYYDDGQN IIKKDIQNMI VEECGCS.

Storage Instruction

For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Repeated freezing and thawing is not recommended.

Sample Prep Instruction

Human INHBA protein should be reconstituted in distilled pyrogen free water to a concentration of 100ug /ml which can then be further diluted to other aqueous solutions.

References

Not Available

View full details

Activin A, Active

SUBHEADING

Recently viewed products