ACP1

Alternative Names: HAAP, MGC3499, MGC111030, ACP1, Low molecular weight phosphotyrosine protein phosphatase, LMW-PTPase, LMW-PTP, Low molecular weight cytosolic acid phosphatase, Red cell acid phosphatase 1, Adipocyte acid phosphatase.

ACP1 is a protein involved in tyrosine phosphorylation. It acts as both an acid phosphatase and a protein tyrosine phosphatase in various human tissues, including adipocytes. ACP1 enzyme functions by breaking down protein tyrosine phosphate into protein tyrosine and orthophosphate, as well as orthophosphoric monoesters into alcohol and orthophosphate. This enzyme is found in adipocytes and plays a role in regulating adipose tissue. High levels of ACP1 have been shown to inhibit cell proliferation and growth of leiomyomas by dephosphorylating the PDGF receptor. Acid phosphatase locus 1 phenotypes have been linked to differences in birth weight-placental weight relationships.

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  • Sku: PSB-enz-408-5µg
  • Vendor: ProSpec-Tany
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Safety Data Sheet
UniProt Listing
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Product Details

Product Description

Recombinant Human Acid Phosphatase-1 is an enzyme belonging to the acid phosphatase family. It plays a significant role in catalyzing the hydrolysis of phosphate esters in acidic conditions. With a molecular weight of approximately 35 kDa, Recombinant Human Acid Phosphatase-1 is commonly used in research and diagnostic applications due to its ability to cleave phosphate groups from a variety of substrates. Its precise enzymatic activity makes it a valuable tool in biochemical studies and drug development.

Current Lead Time

7-14 Days

Product Specifications

Species
 Human
Expression System E. coli
Purity 95% by SDS-PAGE
Activity
 Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
 N/A
Structure Homodimer
Endotoxin Concentration
 Not Available
Purification Method Not Available
Form
 Frozen
Formulation The ACP1 protein solution contains 20mM MES, pH-6, 0.1mM PMSF, 2mM EDTA and 10% Glycerol.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

MGSSHHHHHH SSGLVPRGSH MAEQATKSVL FVCLGNICRS PIAEAVFRKL VTDQNISENW VIDSGAVSDW NVGRSPDPRA VSCLRNHGIHTAHKARQITK EDFATFDYIL CMDESNLRDL NRKSNQVKTC KAKIELLGSY DPQKQLIIED PYYGNDSDFE TVYQQCVRCC RAFLEKAH.

Storage Instruction

Reconstituted store at -20°C or -80°C.We recommend that single use aliquots are prepared to avoid freeze-thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution
​

References

Not Available
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ACP1
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